Fibrillin 抗体
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北京 101111
Quick Overview for Fibrillin 抗体 (ABIN135062)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
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The antibody detects: Human and bovine fibrillin (Mr 350 kDa), other species not tested
In immunohistochemical staining of paraformaldehyde-fixed human skin, mAb 11C1.3 labels the elastic framework and more specifically the oxytalantic network close to the epidermis. The antibody also exhibits discrete staining of normal fibroblasts in culture and of extracellular (elastin) fibrils in a variety of tissues. There is an aberrant expression of fibrillin in Marfan syndrome. -
纯化方法
- Purified
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免疫原
- Microfibrils from zonular apparatus of bovine eye Ig
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亚型
- IgG1
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anti-Fibrillin (FBL) antibody (Biotin)
FBL 适用: Cow, 人 IHC, WB, ICC 宿主: 小鼠 Monoclonal 11C1-3 Biotin
anti-Fibrillin (FBL) antibody (FITC)FBL 适用: Cow, 人 IHC, ICC 宿主: 小鼠 Monoclonal 11C1-3 FITC
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应用备注
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Working Dilution:
Immunohistochemistry: 1:50-1:100 (30-60 min at RT)
Representative data are included in this product insert.
Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. -
样本量
- 1 mL
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限制
- 仅限研究用
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缓冲液
- Product is supplied as 0.2 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.0.
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储存液
- Azide free
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注意事项
- Each reagent is stable for the period shown on the bottle label if stored as directed.
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储存条件
- 4 °C
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- Fibrillin (FBL)
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别名
- Fibrillin
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背景
- The fibrillins are extracellular matrix glycoproteins which occur as a major component of a subset of connective tissue microfibrils. These microfibrils have a beaded appearance and a cross-sectional diameter of 10-12 nm. In elastic tissues, these structures are thought to provide the scaffold onto which elastin is assembled to form elastic fibers, although their function in non-elastic tissues is unclear.
抗原
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