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KDM5B 抗体 (AA 231-319)

Cited in 3+ publications. This 小鼠 单克隆 anti-KDM5B antibody (Clone 1G10) specifically detects KDM5B in WB, ELISA, IF 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN1327126
发货至: 中国
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Quick Overview for KDM5B 抗体 (AA 231-319) (ABIN1327126)

抗原

See all KDM5B 抗体
KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This KDM5B antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

1G10
  • 抗原表位

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    AA 231-319

    原理

    Mouse monoclonal antibody raised against a partial recombinant KDM5B.

    序列

    AKRMRAEAMN IKIEPEETTE ARTHNLRRRM GCPTPKCENE KEMKSSIKQE PIERKDYIVE NEKEKPKSRS KKATNAVDLY VCLLCGSGN

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    KDM5B (NP_006609, 231 a.a. ~ 319 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Mitra, Das, Huynh, Jones: "Jumonji/ARID1 B (JARID1B) protein promotes breast tumor cell cycle progression through epigenetic repression of microRNA let-7e." in: The Journal of biological chemistry, Vol. 286, Issue 47, pp. 40531-5, (2011) (PubMed).

    Hayami, Yoshimatsu, Veerakumarasivam, Unoki, Iwai, Tsunoda, Field, Kelly, Neal, Yamaue, Ponder, Nakamura, Hamamoto: "Overexpression of the JmjC histone demethylase KDM5B in human carcinogenesis: involvement in the proliferation of cancer cells through the E2F/RB pathway." in: Molecular cancer, Vol. 9, pp. 59, (2010) (PubMed).

    Xiang, Zhu, Han, Ye, Xu, Peng, Ma, Yu, Lin, Chen, Chen: "JARID1B is a histone H3 lysine 4 demethylase up-regulated in prostate cancer." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 49, pp. 19226-31, (2007) (PubMed).

  • 抗原

    KDM5B (Lysine (K)-Specific Demethylase 5B (KDM5B))

    别名

    KDM5B

    背景

    Full Gene Name: jumonji, AT rich interactive domain 1B
    Synonyms: FLJ10538,FLJ12459,FLJ12491,FLJ16281,FLJ23670,KDM5B,PLU-1,PUT1,RBBP2H1A

    基因ID

    10765

    NCBI登录号

    NM_006618

    途径

    Warburg Effect
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