KCNT1 抗体 (AA 1168-1237)
Quick Overview for KCNT1 抗体 (AA 1168-1237) (ABIN1304962)
抗原
See all KCNT1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1168-1237
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特异性
- No off-targets reported
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交叉反应
- 人, Marine Mollusks (Liolophura), 小鼠, 大鼠
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产品特性
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Description: Our Anti-Slo2.2/Slack K+ channel mouse monoclonal primary antibody is produced in-house from hybridoma clone N3/26. It is KO validated, detects human, marine mollusk, mouse, and rat Slo2.2/Slack K+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.
Manufacturer Comment: We produce our Slo2.2/Slack K+ channel mouse monoclonal primary antibody from hybridoma clone N3/26. It is great in IHC, ICC, WB and is purified by Protein A chromatography.
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纯化方法
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.
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纯度
- > 90% specific antibody
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免疫原
- Fusion protein amino acids 1168-1237 of rat Slo2.2 (accession number NP_068625) produced recombinantly in E. Coli
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亚型
- IgG1
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应用备注
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Dilution Range: IHC: 1:400
Dilution Range: ICC: 1:250
Dilution Range: WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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有效期
- 24 months
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- KCNT1 (Potassium Channel, Subfamily T, Member 1 (KCNT1))
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别名
- Slo2.2
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背景
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Synonyms: Potassium channel subfamily T member 1 (Sequence like a calcium-activated potassium channel subunit)
Target Description: Potassium channel subfamily T member 1 or -KCNT1/Slo2.2/Slack K+ channel is encoded by the gene KCNT1. Slo2.2 is a member of the the voltage-gated ion channel (vic) superfamily, and the KCNT protein family, which is made of KCNT1 and KCNT2. Slo2.2 functions as an outwardly rectifying potassium channel subunit to contribute to ion conductance and signaling pathways. Slo2.2 can be activated by high intracellular sodium or chloride levels. Slo2.2 is expressed at the membrane in many areas of the brain, brainstem, spinal cord, spleen and liver. Mutations in this gene cause the early-onset epileptic disorders
Gene Name Alternatives: Kcnt1 Slack
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分子量
- 140 kDa
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NCBI登录号
- NP_068625
抗原
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