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DLG4 抗体 (AA 77-299)

Name: DLG4 抗体 (AA 77-299)
SKU: ABIN1304920
Availability: OutOfStock

This anti-DLG4 antibody is a 小鼠单克隆 antibody detecting DLG4 in WB, IHC, ICC 和 IP. Suitable for 人. This Primary Antibody has been cited in 4+ publications.

(4 references)

产品编号 ABIN1304920

发货至: 中国

Quick Overview for DLG4 抗体 (AA 77-299) (ABIN1304920)

抗原

See all DLG4 抗体

DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

适用

人

宿主

小鼠

克隆类型

单克隆

标记

This DLG4 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

克隆位点

K28-43

Discover our top product DLG4 Primary Antibody

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AA 77-299

特异性

No off-targets reported for recombinant Chapsyn-110, SAP97 or SAP102

交叉反应

小鸡, 人, 小鼠, Non-Human Primate, 大鼠

产品特性

Description: Our Anti-PSD 95 mouse monoclonal primary antibody is produced in-house from hybridoma clone K28/43. It is KO validated, detects chicken, human, mouse, non-human primate, and rat PSD 95, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.
Manufacturer Comment: We produce our PSD 95 mouse monoclonal primary antibody from hybridoma clone K28/43. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography.

纯化方法

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.

纯度

> 90% specific antibody

免疫原

Fusion protein amino acids 77-299 (PDZ domains 1 and 2) of human PSD-95 (accession number P78352) produced recombinantly in E. Coli

亚型

IgG2a
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody
DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA, mIHC 宿主: 小鼠 Monoclonal 6G6 unconjugated

anti-Discs, Large Homolog 4 (Drosophila) (DLG4) (C-Term) antibody
DLG4 适用: 大鼠, 人, 小鼠 WB, IHC, ELISA, IF, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody
DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 unconjugated

anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (HRP)
DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 HRP

anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (FITC)
DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 FITC

anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (Biotin)
DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 Biotin

anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (PE)
DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 PE

anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (PerCP)
DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 PerCP

anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (APC)
DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 APC

anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (Atto 488)
DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 Atto 488

应用备注

Dilution Range: IP: 5 μg
Dilution Range: IHC: 1:500
Dilution Range: ICC: 1:500
Dilution Range: WB: 1:1000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

储存条件

4 °C,-20 °C

储存方法

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

有效期

24 months
Madore, Leyrolle, Morel, Rossitto, Greenhalgh, Delpech, Martinat, Bosch-Bouju, Bourel, Rani, Lacabanne, Thomazeau, Hopperton, Beccari, Sere, Aubert, De Smedt-Peyrusse, Lecours, Bisht, Fourgeaud et al.: "Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse developing brain. ..." in: Nature communications, Vol. 11, Issue 1, pp. 6133, (2020) (PubMed).

Gonzalez-Lozano, Klemmer, Gebuis, Hassan, van Nierop, van Kesteren, Smit, Li: "Dynamics of the mouse brain cortical synaptic proteome during postnatal brain development." in: Scientific reports, Vol. 6, pp. 35456, (2016) (PubMed).

Armstrong, Chung, Armstrong, Hochgeschwender, Jeong, Hawkes: "A novel somatostatin-immunoreactive mossy fiber pathway associated with HSP25-immunoreactive purkinje cell stripes in the mouse cerebellum." in: The Journal of comparative neurology, Vol. 517, Issue 4, pp. 524-38, (2009) (PubMed).

Fischer, Foster, Scott, Sherwood: "Transient expression of LIM-domain transcription factors is coincident with delayed maturation of photoreceptors in the chicken retina." in: The Journal of comparative neurology, Vol. 506, Issue 4, pp. 584-603, (2007) (PubMed).
抗原

DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

别名

PSD 95

背景

Synonyms: Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Target Description: PSD-95 is a member of the MAGUK (membrane associated guanylate kinase) family (which also includes PSD-93, SAP97 and SAP102) and functions as a scaffold protein that can cluster membrane receptors, ion channels, including NMDA receptor subunits, Kv1 potassium channels and Caspr2. The protein is encoded by DLG4, contains hallmark PDZ, SH3 and GuK domains and is found at post synaptic densities where it plays an important role in the formation and maintenance of synaptic junctions (Zhou and Blumberg, 2003). Indeed, overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. Antibodies against PSD95/DLG4 are frequently used in conjunction with pre-synaptic markers to localize synapses by microscopy
Gene Name Alternatives: DLG4 PSD95

分子量

95-110 kDa (varies with cell background due to phosphorylation)

UniProt

P78352

途径

Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity