Neuroligin 1 抗体 (AA 718-843)
Quick Overview for Neuroligin 1 抗体 (AA 718-843) (ABIN1304857)
抗原
See all Neuroligin 1 (NLGN1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 718-843
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特异性
- No off-targets reported for Neuroligin-2, -3, -4 or -4*
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交叉反应
- 小鸡, 人, 小鼠, 大鼠
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产品特性
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Description: Our Anti-Neuroligin-1 mouse monoclonal primary antibody is produced in-house from hybridoma clone N97A/31. It is KO validated, detects mouse and rat Neuroligin-1, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.
Manufacturer Comment: We produce our Neuroligin-1 mouse monoclonal primary antibody from hybridoma clone N97A/31. It is great in IHC, ICC, WB and is purified by Protein A chromatography.
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纯化方法
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.
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纯度
- > 90% specific antibody
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免疫原
- Fusion protein amino acids 718-843 (intracellular C-terminus) of rat Neuroligin-1 (accession number NP_446320) produced recombinantly in E. Coli
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亚型
- IgG1
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应用备注
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Dilution Range: IHC: 1:500
Dilution Range: ICC: 1:500
Dilution Range: WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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有效期
- 24 months
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- Neuroligin 1 (NLGN1)
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别名
- Neuroligin-1
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背景
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Synonyms: Neuroligin-1 (Neuroligin I)
Target Description: Neuroligin 1 is a member of a large family of alternatively sliced proteins located at the post synaptic surface in the central nervous system, and stains as a post synaptic marker. Neuroligin 1 is involved in cell-cell-interactions by binding to neurexin family members and other postsynaptic proteins to localize receptors and channels in the postsynaptic density. Suggested roles for Neuroligin 1 include synapse function and synaptic signal transmission and maintaining synapse integrity. Mutations in Neuroligans have been implicated in autism and other cognitive disorders.
Gene Name Alternatives: Nlgn1
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分子量
- 120 kDa
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NCBI登录号
- NP_446320
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途径
- Synaptic Membrane, Synaptic Vesicle Exocytosis
抗原
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