GIT2 抗体 (AA 450-759)
Quick Overview for GIT2 抗体 (AA 450-759) (ABIN1304675)
抗原
See all GIT2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 450-759
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特异性
- No off-targets reported for GIT1
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Description: Our Anti-GIT2 mouse monoclonal primary antibody is produced in-house from hybridoma clone N83/48. It detects human, mouse, and rat GIT2, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.
Manufacturer Comment: We produce our GIT2 mouse monoclonal primary antibody from hybridoma clone N83/48. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography.
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纯化方法
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.
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纯度
- > 90% specific antibody
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免疫原
- Fusion protein amino acids 450-759 (C-terminus) of human GIT2 (accession number Q14161) produced recombinantly in E. Coli
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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有效期
- 24 months
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- GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))
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别名
- GIT2
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背景
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Synonyms: ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2)
Target Description: G-protein coupled receptor kinase interacting ArfGAP 2 is encoded by the gene GIT2. GIT2 is a member of the GIT protein family. GIT2 has a be shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. GIT2 is expressed in 207 organs with the highest expression level in the right hemisphere of cerebellum. Diseases associated with GIT2 include Gastric Antral Vascular Ectasia and Systemic Scleroderma.
Gene Name Alternatives: GIT2 KIAA0148
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分子量
- 85 kDa
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UniProt
- Q14161
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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