DLG2 抗体 (AA 1-852)
Quick Overview for DLG2 抗体 (AA 1-852) (ABIN1304598)
抗原
See all DLG2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-852
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特异性
- No off-targets reported for other MAGUK family members PSD-95, SAP97, SAP102 expressed in transfected cells
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交叉反应
- 人, 小鼠, 兔, 大鼠
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产品特性
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Description: Our Anti-Chapsyn-110/PSD-93 mouse monoclonal primary antibody is produced in-house from hybridoma clone N18/30. It is KO validated, detects human, mouse, rabbit, and rat Chapsyn-110/PSD-93, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.
Manufacturer Comment: We produce our Chapsyn-110/PSD-93 mouse monoclonal primary antibody from hybridoma clone N18/30. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography.
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纯化方法
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.
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纯度
- > 90% specific antibody
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免疫原
- Fusion protein amino acids 1-852 of rat Chapsyn-110 (accession number Q63622) produced recombinantly in E. Coli
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亚型
- IgG1
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anti-Discs, Large Homolog 2 (DLG2) (AA 310-420) antibody
DLG2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large Homolog 2 (DLG2) (N-Term) antibodyDLG2 适用: 人, 大鼠, 小鼠, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large Homolog 2 (DLG2) (AA 614-648) antibodyDLG2 适用: 大鼠, 小鼠 WB 宿主: 兔 Polyclonal RB47835 unconjugated
anti-Discs, Large Homolog 2 (DLG2) (N-Term) antibodyDLG2 适用: 人, 大鼠, 小鼠, 豚鼠, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large Homolog 2 (DLG2) (pTyr340) antibodyDLG2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large Homolog 2 (DLG2) (AA 22-37) antibodyDLG2 适用: 人, 大鼠, 小鼠, Hamster WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Dilution Range: IHC: 1:500
Dilution Range: ICC: 1:100
Dilution Range: WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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有效期
- 24 months
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- DLG2 (Discs, Large Homolog 2 (DLG2))
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别名
- PSD-93
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背景
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Synonyms: Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93)
Target Description: PSD-93/Chapsyn-110 (also known as Channel-associated protein of synapse-110, Postsynaptic density protein PSD-93, Disks large homolog 2 and Dlg2) is a member of the membrane-associated guanylate kinase (MAGUK) family. The protein contains a guanylate kinase-like domain, 3 PDZ domains and 1 SH3 domain. Chapsyn110 binds to NMDA receptor subunits and Shaker K+ channel subunits to aid in forming a multiprotein scaffold which clusters receptors, ion channels, cytoskeletal protiens and other cell signaling proteins. In this manner, it plays a key role in postsynaptic targeting. It is found in brain in neuronal cells and located at the cell synapse, postsynaptic cell membrane and postsynaptic density. Chapsyn110 has been implicated in chronic pain, bilateral retinoblastoma and schizophrenia.
Gene Name Alternatives: Dlg2 Dlgh2
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分子量
- 110 kDa
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UniProt
- Q63622
抗原
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