CNTNAP2 抗体 (Extracellular Domain)
Quick Overview for CNTNAP2 抗体 (Extracellular Domain) (ABIN1304573)
抗原
See all CNTNAP2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Extracellular Domain
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特异性
- No off-targets reported for Caspr/paranodin
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Description: Our Anti-CASPR2 mouse monoclonal primary antibody is produced in-house from hybridoma clone K67/25. It is KO validated, detects human, mouse, and rat CASPR2, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.
Manufacturer Comment: We produce our CASPR2 mouse monoclonal primary antibody from hybridoma clone K67/25. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography.
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纯化方法
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.
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纯度
- > 90% specific antibody
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免疫原
- Fusion protein 96-1265 (extracellular domain) of human Caspr2 (accession number A0A090N7T7) produced recombinantly in E. Coli
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亚型
- IgG2a
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anti-Contactin Associated Protein-Like 2 (CNTNAP2) (AA 1-1331) antibody
CNTNAP2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Contactin Associated Protein-Like 2 (CNTNAP2) (AA 801-900) antibodyCNTNAP2 适用: 人, 大鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Contactin Associated Protein-Like 2 (CNTNAP2) (AA 1-1331) antibodyCNTNAP2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Contactin Associated Protein-Like 2 (CNTNAP2) (AA 1079-1106) antibodyCNTNAP2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB22699 unconjugated
anti-Contactin Associated Protein-Like 2 (CNTNAP2) (Extracellular Domain) antibodyCNTNAP2 适用: 人 WB, IHC, IP, FM 宿主: 小鼠 Monoclonal S67-25 unconjugated
anti-Contactin Associated Protein-Like 2 (CNTNAP2) (AA 1315-1331), (Intracellular) antibodyCNTNAP2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Dilution Range: IHC: 1:100
Dilution Range: WB: 1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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有效期
- 24 months
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- CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))
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别名
- CASPR2
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背景
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Synonyms: Contactin associated protein-like 2 (Contactin associated protein-like 2, isoform CRA_b)
Target Description: Contactin-associated protein-like 2 protein, or Caspr2, is a neuronal transmembrane member of the Neurexin family. Structural features of Caspr2 include epidermal growth factor repeats, laminin G domains, F5/8 type C domain, fibrinogen-like domains, and PDZ binding sites. Caspr2 is a cell adhesion molecule as well as a receptor. It is involved in mediating cell-cell interactions in the nervous system and involved in neural-glia interactions and clustering of potassium channels in myelinated axons. It is expressed at the juxaperanodal region of nodes of Ranvier in the CNS and PNS. Changes in expression have been associated with increased susceptibility to autism and epilepsy.
Gene Name Alternatives: CNTNAP2 hCG_15499 tcag7.496
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分子量
- 180 kDa
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NCBI登录号
- NP_054860
抗原
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