ANK2 抗体 (AA 203-496)
Quick Overview for ANK2 抗体 (AA 203-496) (ABIN1304532)
抗原
See all ANK2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 203-496
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特异性
- No off-targets reported
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交叉反应
- Cow, 豚鼠, 人, 小鼠, 大鼠
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产品特性
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Description: Our Anti-Ankyrin-B mouse monoclonal primary antibody is produced in-house from hybridoma clone N105/13. It detects human, mouse, and rat Ankyrin-B, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.
Manufacturer Comment: We produce our Ankyrin-B mouse monoclonal primary antibody from hybridoma clone N105/13. It is great in IHC, ICC, WB and is purified by Protein A chromatography.
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纯化方法
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.
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纯度
- > 90% specific antibody
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免疫原
- Fusion protein amino acids 203-496 of human Ankyrin-B (accession number Q01484) produced recombinantly in E. Coli
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亚型
- IgG1
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应用备注
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Dilution Range: IP: 3 μg
Dilution Range: IHC: 1:500
Dilution Range: ICC: 1:500
Dilution Range: WB: 1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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有效期
- 24 months
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- ANK2 (Ankyrin 2, Neuronal (ANK2))
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别名
- Ankyrin-B
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背景
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Synonyms: Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin)
Target Description: Ankyrin-2 or -Ankyrin-B is encoded by the gene ANK2. Ankyrin B is a scaffold protein that functions to link proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane cytoskeleton. In this manner, ankyrin family proteins play key roles in various processes including cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Ankyrin B is expressed in brain and muscle. Mutations in this gene cause long QT syndrome 4 and cardiac arrhythmia syndrome.
Gene Name Alternatives: ANK2 ANKB
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分子量
- > 200 kDa
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UniProt
- Q01484
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途径
- Cell-Cell Junction Organization
抗原
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