ADAM22 抗体 (AA 757-857)
Quick Overview for ADAM22 抗体 (AA 757-857) (ABIN1304517)
抗原
See all ADAM22 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 757-857
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特异性
- No off-targets reported
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
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Description: Our Anti-ADAM22 (cytoplasmic) mouse monoclonal primary antibody is produced in-house from hybridoma clone N46/30. It is KO validated, detects human, mouse, and rat ADAM22 (cytoplasmic), and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.
Manufacturer Comment: We produce our ADAM22 (cytoplasmic) mouse monoclonal primary antibody from hybridoma clone N46/30. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography.
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纯化方法
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.
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纯度
- > 90% specific antibody
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免疫原
- Fusion protein amino acids 757-857 (cytoplasmic region) of mouse ADAM22 (accession number Q9R1V6) produced recombinantly in E. Coli
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亚型
- IgG2b
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应用备注
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Dilution Range: IP: 1:250
Dilution Range: IHC: 1:100
Dilution Range: ICC: 1:100
Dilution Range: WB: 1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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有效期
- 24 months
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- ADAM22 (ADAM Metallopeptidase Domain 22 (ADAM22))
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别名
- ADAM22
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背景
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Synonyms: Disintegrin and metalloproteinase domain-containing protein 22 (ADAM 22)
Target Description: ADAM22 is a member of the ADAM (a disintegrin and metalloproteinase) family and predominantly expressed in brain. ADAM 22 is non-catalytic unlike other proteins in the family as it does not contain a zinc binding domain. ADAM22 is a post synaptic neuron receptor for LGI 1 and also binds LGI4. ADAM22 serve as an integrin ligand. Mutations in ADAM22 are implicated in early infantile epileptic encephalopathy-61 and Brachydactyly type C.
Gene Name Alternatives: Adam22
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分子量
- 90 kDa
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UniProt
- Q9R1V6
抗原
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