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DPP4 抗体 (APC)

This anti-DPP4 antibody is a 小鼠 单克隆 antibody detecting DPP4 in FACS. Suitable for 人.
产品编号 ABIN1302631
发货至: 中国

Quick Overview for DPP4 抗体 (APC) (ABIN1302631)

抗原

See all DPP4 抗体
DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

适用

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宿主

  • 93
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小鼠

克隆类型

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单克隆

标记

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This DPP4 antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)

克隆位点

BA5b
  • 原理

    Anti-Hu CD26 APC

    特异性

    The mouse monoclonal antibody BA5b recognizes an extracellular epitope of CD26, a 110 kDa type II transmembrane glycoprotein, which is a peptidase expressed on mature thymocytes, T cells (especially activated), B cells, NK cells and macrophages.

    交叉反应 (详细)

    Human

    纯化方法

    Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    免疫原

    A human T cell clone

    亚型

    IgG2a kappa
  • 应用备注

    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

    限制

    仅限研究用
  • 溶解方式

    No reconstitution is necessary.

    缓冲液

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.
    Avoid prolonged exposure to light.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原

    DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

    别名

    CD26

    背景

    Dipeptidyl peptidase 4,CD26, also known as dipeptidyl peptidase IV (DPP-IV), is a homodimeric cell surface serine peptidase that degradates IFN-gamma-induced cytokines, acts as a T cell costimulatory molecule, and participates in multiple immunopathological roles in leukocyte homing and inflammation. Alterations in its peptidase activity are characteristic of malignant transformation. The enzymatic activity increases dramatically with tumour grade and severity. CD26 is expressed in various blood cell types, but also e.g. in cells that are histogenetically related to activated fibroblasts. Alterations in CD26 density have been reported on circulating monocytes and CD4+ T cells during rheumatoid arthritis and systemic lupus erythematosus.,DPP4, TP103, ADCP-2, ADABP

    基因ID

    1803

    UniProt

    P27487

    途径

    Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity
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