PDGFRB 抗体 (APC)
(1 reference)Quick Overview for PDGFRB 抗体 (APC) (ABIN1302625)
抗原
See all PDGFRB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD140b APC
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特异性
- The monoclonal antibody 18A2 recognizes an extracellular epitope of CD140b / PDGF-RB, the 180-190 kDa beta chain of platelet-derived growth factor receptor, which is widely expressed on a variety of mesenchymal-derived cells and plays pro-proliferative roles.
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交叉反应 （详细）
- Human
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纯化方法
- Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- CD140b-transfected NIH 3T3 cells
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亚型
- IgG1
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anti-Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 33-133) antibody
PDGFRB 适用: 人 WB, ELISA, IP, PLA 宿主: 小鼠 Monoclonal 4C12 unconjugated
anti-Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 887-1106) antibodyPDGFRB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 981-1066) antibodyPDGFRB 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 1-1106) antibodyPDGFRB 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 40-72) antibodyPDGFRB 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 33-133) antibodyPDGFRB 适用: 人, 小鼠 ELISA, FACS 宿主: 小鼠 Monoclonal 2G7B7 unconjugated
anti-Platelet Derived Growth Factor Receptor beta (PDGFRB) antibodyPDGFRB 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 1G9 unconjugated
anti-Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 1-1106) antibodyPDGFRB 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor beta (PDGFRB) antibodyMicroarray verified PDGFRB 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB472367 unconjugated
anti-Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 718-767) antibodyPDGFRB 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
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限制
- 仅限研究用
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溶解方式
- No reconstitution is necessary.
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缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
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Do not freeze.
Avoid prolonged exposure to light. -
储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "GMP-compliant isolation and large-scale expansion of bone marrow-derived MSC." in: PLoS ONE, Vol. 7, Issue 8, pp. e43255, (2012) (PubMed).
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: "GMP-compliant isolation and large-scale expansion of bone marrow-derived MSC." in: PLoS ONE, Vol. 7, Issue 8, pp. e43255, (2012) (PubMed).
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- PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
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别名
- CD140b
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背景
- Platelet derived growth factor receptor beta,CD140b / PDGF-RB (platelet-derived growth factor receptor beta) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140b forms homodimers, or heterodimerizes with CD140a / PDGF-RA. Whereas CD140a can have both pro-proliferative or anti-proliferative effects, the CD140b induces in various cell types their proliferation and migration. CD140b has also developmental roles in the cardiovascular system and is preferentially expressed on some tumours such as medulloblastoma.,PDGFRB, PDGFR1
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基因ID
- 5159
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UniProt
- Q59F04
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
抗原
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