CD161 抗体
(4 references)Quick Overview for CD161 抗体 (ABIN1302471)
抗原
See all CD161 (KLRB1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Rt CD161 Purified
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特异性
- The mouse monoclonal antibody 10/78 recognizes CD161, an approximately 30 kDa type II transmembrane C-type lectin receptor, expressed on the plasma membrane of NK cells, dendritic cells, activated monocytes and a subset of T cells as a disulphide-linked homodimer. A common extracellular epitope on rat CD161a and b isoforms is detected.
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交叉反应 （详细）
- Rat
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- Splenic cells purified from the LEW rat
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亚型
- IgG1 kappa
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anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) (AA 73-188) antibody
KLRB1 适用: 人 WB, IP, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) antibodyKLRB1 适用: 人, Non-Human Primate FACS, WB, IHC (fro) 宿主: 小鼠 Monoclonal HP-3G10 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) antibody (PE)KLRB1 适用: 大鼠 FACS 宿主: 小鼠 Monoclonal 10-78 PE
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) (AA 67-225) antibodyKLRB1 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 4C6A11 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) (AA 151-225) antibodyKLRB1 适用: 人, 大鼠 ELISA 宿主: 兔 Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) antibody (FITC)KLRB1 适用: 大鼠 FACS 宿主: 小鼠 Monoclonal 10-78 FITC
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) antibodyKLRB1 适用: 大鼠 FACS, WB, IP, IHC (fro), RIA 宿主: 小鼠 Monoclonal 10-78 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) (AA 126-225) antibodyKLRB1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F3 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) antibody (PE)KLRB1 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal HP-3G10 PE
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) (AA 73-140) antibodyKLRB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow cytometry: Recommended dilution: 1-4 μg/mL.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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: "Phenotypic characterization of regulatory CD4+CD25+ T cells in rats." in: International immunology, Vol. 16, Issue 2, pp. 365-75, (2004) (PubMed).
: "CD8 alpha beta T cells are not essential to the pathogenesis of arthritis or colitis in HLA-B27 transgenic rats." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 2, pp. 1099-105, (2003) (PubMed).
: "Evaluation of the hepatic NK cell response during the early phase of Fasciola hepatica infection in rats." in: Veterinary research, Vol. 33, Issue 3, pp. 327-32, (2002) (PubMed).
: "Negative regulation of rat natural killer cell activity by major histocompatibility complex class I recognition." in: European journal of immunology, Vol. 26, Issue 11, pp. 2582-6, (1997) (PubMed).
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: "Phenotypic characterization of regulatory CD4+CD25+ T cells in rats." in: International immunology, Vol. 16, Issue 2, pp. 365-75, (2004) (PubMed).
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- CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))
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别名
- CD161
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背景
- Killer cell lectin-like receptor subfamily B, memb,CD161, also known as Nkrp1 (natural killer receptor protein 1) or Klrb1 (killer cell lectin-like receptor subfamily b member 1), is a disulphide-linked homodimeric receptor, which is involved in regulation of NK cell and NKT cell function. It is expressed on rat NK cells, subset of T cells, dendritic cells, and activated monocytes. Although human CD161 is expressed as one isoform, the rat CD161 has three isoforms, referred to as CD161a, b, and c. These proteins contain C-terminal C-type lectin extracellular domain, a transmembrane domain, and N-terminal intracellular domain, which contains ITIM motif, such as CD161b, and displays inhibitory function, or does not contain ITIM motif, thus also not the inhibitory function, such as CD161a.,NKRP1A, Klrb
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基因ID
- 689817
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UniProt
- Q0ZUP0
抗原
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