SLIT1 抗体 (AA 485-515)
Quick Overview for SLIT1 抗体 (AA 485-515) (ABIN129640)
抗原
See all SLIT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 485-515
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Supplier Product No.
- 600-401-860
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Supplier
- Rockland
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原理
- Slit1 Antibody
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交叉反应 （详细）
- This affinity purified antibody is directed against mouse SLIT-1 protein.
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产品特性
- Synonyms: rabbit anti-Slit-1 antibody, Slit1, Slit 1, Slit homolog 1 protein
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纯化方法
- The product was affinity purified from monospecific antiserum by immunoaffinity purification.
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过滤
- Sterile filtered
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免疫原
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Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near aa 485-515 of mouse SLIT-1 protein.
Immunogen Type: Conjugated Peptide
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亚型
- IgG
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anti-Slit Homolog 1 (SLIT1) (AA 647-835) antibody
SLIT1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Slit Homolog 1 (SLIT1) (AA 603-773) antibodySLIT1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Slit Homolog 1 (SLIT1) (AA 308-512) antibodySLIT1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Slit Homolog 1 (SLIT1) (AA 84-113) antibodySLIT1 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Slit Homolog 1 (SLIT1) (AA 611-791) antibodySLIT1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Slit Homolog 1 (SLIT1) (AA 455-500) antibodySLIT1 适用: 人 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Slit Homolog 1 (SLIT1) (AA 1439-1488) antibodySLIT1 适用: 人, Cow, 犬, 马, Pig, 兔, 斑马鱼, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Slit Homolog 1 (SLIT1) (AA 1315-1534) antibodySLIT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Slit Homolog 1 (SLIT1) (AA 345-623) antibodySLIT1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Slit Homolog 1 (SLIT1) (AA 3-211) antibodySLIT1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Application Note: This affinity purified antibody has been tested for use in ELISA and by western blot. Specific conditions for reactivity should be optimized by the end user. Expect multiple bands corresponding to cleavage products of SLIT-1 by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1:500 - 1:2,000
ELISA Dilution: 1:10,000 - 1:50,000
Other: User Optimized
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.2 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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- SLIT1 (Slit Homolog 1 (SLIT1))
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别名
- Slit1
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背景
- Background: SLIT-1 (also known as KIAA0813, MEGF4, multiple epidermal growth factor-like domains 4 and Slit homolog 1 protein) is a Slit protein. This protein is a ligand for the Roundabout (Robo) receptors and acts as guidance cues in axonal migration/navigation during neural development, at the ventral midline of the neural tube. Slit1 and Slit2 are essential for midline guidance in the forebrain by acting as repulsive signals preventing inappropriate midline crossing by axons projecting from the olfactory bulb. Each SLIT gene encodes a putative secreted protein, which contains conserved protein-protein interaction domains including leucine-rich repeats and epidermal growth factor-like motifs, similar to those of the Drosophila protein. In situ hybridization studies indicated that the rat SLIT-1 mRNA was specifically expressed in the neurons of fetal and adult forebrains. This data suggests that the SLIT genes form an evolutionarily conserved group in vertebrates and invertebrates, and that the mammalian SLIT proteins may participate in the formation and maintenance of the nervous and endocrine systems by protein-protein interactions. Alternative splicing isoforms have been identified for Slit1 protein.
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基因ID
- 20562, 256355216
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UniProt
- Q80TR4
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途径
- Regulation of Cell Size
抗原
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