ING5 抗体 (AA 125-150)
(1 reference)
Quick Overview for ING5 抗体 (AA 125-150) (ABIN129552)
抗原
See all ING5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 125-150
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Supplier Product No.
- 600-101-285
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Supplier
- Rockland
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原理
- p28ING5 Antibody
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交叉反应 （详细）
- Reactivity occurs against human p28 ING5 protein.
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产品特性
- Synonyms: goat anti-p28 ING5 Antibody, p28ING5, ING-5 antibody, ING 5, Inhibitor of growth family member 5 antibody
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纯化方法
- This is an affinity purified antibody produced by immunoaffinity chromatography using the immunizing peptide after immobilization to a solid phase.
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过滤
- Sterile filtered
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免疫原
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Immunogen: This affinity purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near aa 125-150 of Human p28 ING5 protein (Inhibitor of growth family, member 5).
Immunogen Type: Conjugated Peptide
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亚型
- IgG
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anti-Inhibitor of Growth Family, Member 5 (ING5) (AA 1-240) antibody
ING5 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 5 (ING5) (AA 1-220) antibodyING5 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 5 (ING5) (AA 32-207) antibodyING5 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 5 (ING5) (AA 24-84) antibodyING5 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 5 (ING5) (AA 35-84) antibodyING5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 5 (ING5) antibodyING5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Growth Family, Member 5 (ING5) antibodyING5 适用: 人, 小鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Application Note: This affinity purified antibody has been tested for use in ELISA and by western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 28 kDa or 26 kDa in size corresponding to variants of ING5 by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1:500 - 1:1,000
ELISA Dilution: 1:4,000 - 1:16,000
Other: User Optimized
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.52 mg/mL
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缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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有效期
- 12 months
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: "Hbo1 Links p53-dependent stress signaling to DNA replication licensing." in: Molecular and cellular biology, Vol. 28, Issue 1, pp. 140-53, (2007) (PubMed).
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: "Hbo1 Links p53-dependent stress signaling to DNA replication licensing." in: Molecular and cellular biology, Vol. 28, Issue 1, pp. 140-53, (2007) (PubMed).
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- ING5 (Inhibitor of Growth Family, Member 5 (ING5))
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别名
- ING5
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背景
- Background: p28 ING5 is a tumor suppressor protein similar to ING1 that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed. The accession number listed below is for variant (1) encodes the longest isoform.
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基因ID
- 84289, 18644730
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UniProt
- Q8WYH8
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途径
- Chromatin Binding
抗原
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