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Integrin Alpha2b 抗体 (FITC)

This anti-Integrin Alpha2b antibody is a 小鼠 单克隆 antibody detecting Integrin Alpha2b in FACS, IF 和 IHC (fro). Suitable for 人.
产品编号 ABIN127332
发货至: 中国

Quick Overview for Integrin Alpha2b 抗体 (FITC) (ABIN127332)

抗原

See all Integrin Alpha2b (CD41) 抗体
Integrin Alpha2b (CD41)

适用

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小鼠

克隆类型

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单克隆

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This Integrin Alpha2b antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

SZ-22
  • 产品特性

    Molar Ratio: 15-25 moles of FITC per mole Ig.

    纯化方法

    Ion Exchange or Affinity Chromatography.

    免疫原

    Washed Human platelets. Remarks: Myeloma cells with spleen cells from Balb/c mice.

    亚型

    IgG1
  • 应用备注

    Studies of platelet functions. Identification of gpIIb. Immunohistochemistry on frozen sections or cell smears: 1: 50-1: 100 dilution. Fluorescence Microscopy or Flow Cytometry (20 l/10^6 platelets/test).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 2 mg/mL BSA as stabilizer and 0.09 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • 抗原

    Integrin Alpha2b (CD41)

    别名

    CD41 / ITGA2B

    背景

    The CD41 antigen (platelet GPIIb, alpha IIb integrin) is a Glycoprotein composed of 2 chains, GPIIb alpha (120 kDa) and GPIIb beta (23 kDa), linked by one disulfide bond. (1) CD41 is always non-covalently associated with CD61 (platelet GPIIIa, beta 3 integrin), to form the GPIIb-IIIa (CD41/CD61) complex. The structure and role of the complex CD41/CD61 in hemostasis is reviewed in Ref.2. CD41 is expressed by platelets, Megakaryocytes and by a small subset of CD34+ cells suggesting that CD41/CD61 is the earliest marker of the Megakaryocytic lineage. (3) It has been assigned to the CD41 cluster of differentiation at the 5th International Workshop on Human Leucocyte Differentiation Antigens in Boston, in 1993.Synonyms: GP2B, GPalpha IIb, ITGAB, Integrin alpha-IIb, Platelet membrane glycoprotein IIb

    基因ID

    9606

    UniProt

    P08514

    途径

    Integrin Complex
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