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BIN1 抗体

This 兔 多克隆 antibody specifically detects BIN1 in WB. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN127306
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for BIN1 抗体 (ABIN127306)

抗原

See all BIN1 抗体
BIN1 (Bridging Integrator 1 (BIN1))

适用

  • 78
  • 41
  • 23
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 62
  • 17
  • 1

克隆类型

  • 44
  • 36
多克隆

标记

  • 53
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
This BIN1 antibody is un-conjugated

应用范围

  • 66
  • 45
  • 35
  • 30
  • 23
  • 22
  • 20
  • 6
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 特异性

    The antibody recognizes ~65 kDa band of BIN-1. A cleavage fragment (~45 kDa) can also be detected in apoptotic samples.

    纯化方法

    Immunoaffinity

    免疫原

    Synthetic peptide corresponding to residues surrounding amino acids 578 of mouse BIN-1
  • 应用备注

    Western Blot: 0.5-4 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    PBS containing 0.1 % BSA, 30 % glycerol, and 0.01 % thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    BIN1 (Bridging Integrator 1 (BIN1))

    别名

    BIN1 / AMPHL

    背景

    BIN-1 is a tumor suppressor protein that was identified in a genetic screen for proteins that interact with the MCY oncoprotein. BIN-1 inhibits the oncogenic activity of MYC, possibly through activating or facilitating apoptosis. BIN is a short-lived protein with a half-life of about 2 hours.Synonyms: Amphiphysin II, Amphiphysin-like protein, Box-dependent myc-interacting protein 1, Bridging integrator 1, Myc box-dependent-interacting protein 1

    基因ID

    274

    NCBI登录号

    NP_004296

    UniProt

    O00499
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