BIN1 抗体
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北京 101111
Quick Overview for BIN1 抗体 (ABIN127306)
抗原
See all BIN1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The antibody recognizes ~65 kDa band of BIN-1. A cleavage fragment (~45 kDa) can also be detected in apoptotic samples.
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纯化方法
- Immunoaffinity
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免疫原
- Synthetic peptide corresponding to residues surrounding amino acids 578 of mouse BIN-1
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应用备注
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Western Blot: 0.5-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.2 mg/mL
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缓冲液
- PBS containing 0.1 % BSA, 30 % glycerol, and 0.01 % thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- BIN1 (Bridging Integrator 1 (BIN1))
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别名
- BIN1 / AMPHL
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背景
- BIN-1 is a tumor suppressor protein that was identified in a genetic screen for proteins that interact with the MCY oncoprotein. BIN-1 inhibits the oncogenic activity of MYC, possibly through activating or facilitating apoptosis. BIN is a short-lived protein with a half-life of about 2 hours.Synonyms: Amphiphysin II, Amphiphysin-like protein, Box-dependent myc-interacting protein 1, Bridging integrator 1, Myc box-dependent-interacting protein 1
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基因ID
- 274
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NCBI登录号
- NP_004296
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UniProt
- O00499
抗原
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