MAPK8IP1 抗体
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北京 101111
Quick Overview for MAPK8IP1 抗体 (ABIN127294)
抗原
See all MAPK8IP1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The antibody recognizes 78 kDa JIP1.
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纯化方法
- Protein A purified
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免疫原
- Synthetic peptide from mouse JIP1.
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anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (AA 470-498), (C-Term) antibody
MAPK8IP1 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB23000 unconjugated
anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) antibodyMAPK8IP1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (Tyr466) antibodyMAPK8IP1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (AA 69-118) antibodyMAPK8IP1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) antibodyMAPK8IP1 适用: 人 WB, IHC, FACS, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (AA 425-524) antibodyMAPK8IP1 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (AA 265-279) antibodyVerified MAPK8IP1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (pThr103) antibodyMAPK8IP1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (pThr103) antibodyMAPK8IP1 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (AA 470-498) antibodyMAPK8IP1 适用: 人 WB, IF, IHC, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 0.5-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 2 mg/mL
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缓冲液
- PBS containing 0.5 % BSA, 30 % glycerol, and 0.01 % thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C/-80 °C
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储存方法
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- MAPK8IP1 (Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1))
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别名
- MAPK8IP1 / JIP1
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背景
- JIP1 (JNK-interacting protein-1) is a cytoplasmic protein that possesses an N-terminal JNKbinding domain and a C-terminal SRC homology 3 (SH3) domain. JIP1 selectively bind to JNK, but not to the ERK or p38 MAP kinases. In addition to JNK, JIP1 binds to specific proteins of JNK pathways, including MKK7, MLK3, and DLK, all at separate binding sites. JIP1 has been identified in brain and kidney tissues, whereas JIP2a, JIP2b, and JIP3 are specifically expressed in the brain. Overexpression of JIP1 causes cytoplamic retention of JNK, thereby preventing its nuclear accumulation and the subsequent activation of the JNK pathways, indicating that JIP1 acts as a cytoplasmic anchor for JNK.Synonyms: C-jun-amino-terminal kinase-interacting protein 1, IB1, Islet-brain 1, JIP-1, JNK MAP kinase scaffold protein 1, JNK-interacting protein 1, Mitogen-activated protein kinase 8-interacting protein 1, PRKM8IP
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基因ID
- 9479
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NCBI登录号
- NP_005447
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UniProt
- Q9UQF2
抗原
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