Western blotting (0.5-4 μg/mL). Mouse small intestine tissue lysate can be use as apositive control. Based on researchers feedback, this antibody can also be used inimmunoprecipitation (20-40 μg/mL) and immunohistochemistry (20-40 μg/mL). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
-20 °C/-80 °C
储存方法
Store (in aliquots) at -20 °C to -70 °C.
抗原
HDAC7
(Histone Deacetylase 7 (HDAC7))
别名
HDAC7
背景
Human HDAC7 is composed of 912 amino acid residues. Although HDAC7 is localized mostly to the cell nucleus, it is also found in the cytoplasm, suggesting nucleo-cytoplasmic shuttling. The histone deacetylase activity of HDAC7 maps to a carboxy-terminal domain and is dependent on interaction with class I HDACs in the nucleus. HDAC7 catalyzes removal of acetyl-groups from acetyl-lysines of histones and promotes compaction of chromatin in these regions, leading to the inhibition of gene transcription.Synonyms: HD7, HD7a, HDAC7A, Histone deacetylase 7