HDAC7 抗体
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Quick Overview for HDAC7 抗体 (ABIN127244)
抗原
See all HDAC7 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The antibody detects ~105 kDa HDAC7.
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纯化方法
- Affinity Purified
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免疫原
- Synthetic peptide surrounding amino acid 921 of murine HDAC7
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应用备注
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Western blotting (0.5-4 μg/mL). Mouse small intestine tissue lysate can be use as apositive control. Based on researchers feedback, this antibody can also be used inimmunoprecipitation (20-40 μg/mL) and immunohistochemistry (20-40 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.2 mg/mL
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缓冲液
- PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C/-80 °C
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储存方法
- Store (in aliquots) at -20 °C to -70 °C.
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- HDAC7 (Histone Deacetylase 7 (HDAC7))
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别名
- HDAC7
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背景
- Human HDAC7 is composed of 912 amino acid residues. Although HDAC7 is localized mostly to the cell nucleus, it is also found in the cytoplasm, suggesting nucleo-cytoplasmic shuttling. The histone deacetylase activity of HDAC7 maps to a carboxy-terminal domain and is dependent on interaction with class I HDACs in the nucleus. HDAC7 catalyzes removal of acetyl-groups from acetyl-lysines of histones and promotes compaction of chromatin in these regions, leading to the inhibition of gene transcription.Synonyms: HD7, HD7a, HDAC7A, Histone deacetylase 7
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基因ID
- 51564
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NCBI登录号
- NP_001091886
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UniProt
- Q8WUI4
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途径
- Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development
抗原
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