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HDAC3 抗体 (C-Term)

The 兔 多克隆 anti-HDAC3 antibody (ABIN127236) specifically detects HDAC3 in WB 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN127236
发货至: 中国
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Quick Overview for HDAC3 抗体 (C-Term) (ABIN127236)

抗原

See all HDAC3 抗体
HDAC3 (Histone Deacetylase 3 (HDAC3))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This HDAC3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    C-Term

    特异性

    The antibody detects the 49 kDa HDAC3. It does not cross-react with other HDAC proteins including HDAC1, 2, 4, 5, 6, 7, and 8.

    纯化方法

    Peptide affinity purified.

    免疫原

    Synthetic peptide corresponding to the C-terminus of human HDAC-3.
  • 应用备注

    Western Blot: 0.5-4 μg/mL. Immunohistochemistry: 20-30 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    PBS containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C/-80 °C

    储存方法

    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
  • 抗原

    HDAC3 (Histone Deacetylase 3 (HDAC3))

    别名

    HDAC3

    背景

    HDAC3 is a member of the class I mammalian histone deacetylase family, which plays an important role in modulating the eukaryotic chromatin structure. Human HDAC3 is composed of 428 amino acid residues. HDAC3 interacts with a growing number of transcriptional factors including SMRT and N-CoR. The interacting complexes bind to specific regions of chromatin and regulate gene transcription in these regions.Synonyms: HD3, Histone deacetylase 3, RPD3-2, SMAP45

    基因ID

    8841

    NCBI登录号

    NP_003874

    UniProt

    O15379

    途径

    Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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