LIMK2 抗体 (C-Term)
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Quick Overview for LIMK2 抗体 (C-Term) (ABIN127209)
抗原
See all LIMK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- The antibody detects 70 kDa LIMK2 protein. It does not cross-react with LIMK1. The antibody recognizes ~35 kDa PHAP III.
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纯化方法
- Affinity Purified
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免疫原
- Synthetic peptide corresponding to the C-terminus of human LIMK2.
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应用备注
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Western Blot: 1-4 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C/-80 °C
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储存方法
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- LIMK2 (LIM Domain Kinase 2 (LIMK2))
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别名
- LIMK2
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背景
- LIM kinases (LIMK1 and LIMK2) are serine/threnine kinases that have two zinc finger motifs, known as LIM motifs in their N-terminal regulatory domain. LIM kinases are involved in actin cytoskeleton regulation through Rho-family GTPases and downstream kinases PAKs and ROCK. PAK1 and ROCK phosphorylate LIMK1 and LIMK2, which increases the activity of the kinases. Activated LIM kinases inhibit the actin depolymerization activity of cofilin by phosphorylation at the N-terminus of Cofilin.Synonyms: EC=2.7.11.1, LIM domain kinase 2, LIMK-2, LIMK2
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基因ID
- 3985
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NCBI登录号
- NP_005560
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UniProt
- P53671
抗原
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