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LIMK2 抗体 (C-Term)

This anti-LIMK2 antibody is a 兔 多克隆 antibody detecting LIMK2 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN127209
发货至: 中国

Quick Overview for LIMK2 抗体 (C-Term) (ABIN127209)

抗原

See all LIMK2 抗体
LIMK2 (LIM Domain Kinase 2 (LIMK2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This LIMK2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    特异性

    The antibody detects 70 kDa LIMK2 protein. It does not cross-react with LIMK1. The antibody recognizes ~35 kDa PHAP III.

    纯化方法

    Affinity Purified

    免疫原

    Synthetic peptide corresponding to the C-terminus of human LIMK2.
  • 应用备注

    Western Blot: 1-4 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C/-80 °C

    储存方法

    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
  • 抗原

    LIMK2 (LIM Domain Kinase 2 (LIMK2))

    别名

    LIMK2

    背景

    LIM kinases (LIMK1 and LIMK2) are serine/threnine kinases that have two zinc finger motifs, known as LIM motifs in their N-terminal regulatory domain. LIM kinases are involved in actin cytoskeleton regulation through Rho-family GTPases and downstream kinases PAKs and ROCK. PAK1 and ROCK phosphorylate LIMK1 and LIMK2, which increases the activity of the kinases. Activated LIM kinases inhibit the actin depolymerization activity of cofilin by phosphorylation at the N-terminus of Cofilin.Synonyms: EC=2.7.11.1, LIM domain kinase 2, LIMK-2, LIMK2

    基因ID

    3985

    NCBI登录号

    NP_005560

    UniProt

    P53671
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