MMP13 抗体
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北京 101111
Quick Overview for MMP13 抗体 (ABIN127179)
抗原
See all MMP13 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The antibody recognizes the proenzyme (~60 kDa) and the cleaved fragments (34 kDa and 48 kDa) of MMP-13.
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交叉反应 (详细)
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Species reactivity (expected):Mouse, Rat, Equine (Horse), Rabbit and Bovine.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography.
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免疫原
- Synthetic peptide surrounding amino acid 454 of Rat MMP-13.
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应用备注
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Western blotting (0.5-4 μg/mL) . Immunoprecipitation. Immunohistochemistry (works with Paraffin Embedded Sections).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 30 % Glycerol, 0.5 % BSA and 0.01 % Thimerosal.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C/-80 °C
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储存方法
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))
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别名
- MMP-13
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背景
- The Matrix Metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-13 (also designated collagenase-3) is produced by breast carcinomas and degrades collagen type I, II, III.Synonyms: Collagenase 3, MMP13, Matrix metalloproteinase-13
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基因ID
- 4322
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NCBI登录号
- NP_002418
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UniProt
- P45452
抗原
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