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CCR1 抗体

This 兔 多克隆 antibody specifically detects CCR1 in WB. It exhibits reactivity toward 人.
产品编号 ABIN127096
发货至: 中国
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北京 101111
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CCR1 抗体 (ABIN127096)

抗原

See all CCR1 抗体
CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

适用

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宿主

  • 45
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克隆类型

  • 46
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多克隆

标记

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This CCR1 antibody is un-conjugated

应用范围

  • 37
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Western Blotting (WB)
  • 特异性

    The anti-CCR1 antibody recognizes 42 kDa CCR1 in Western blot analysis.

    纯化方法

    Protein G purified

    免疫原

    Recombinant human CCR1
  • 应用备注

    Western Blot: 1-4 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS containing 50 % glycerol, 1 % BSA, and 0.02 % thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C/-80 °C

    储存方法

    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
  • 抗原

    CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

    别名

    CD191 / CCR1

    背景

    Chemokines play an important role in inflammation and are critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR1, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils and binds the leukocyte chemoattractant and hemopoiesis regulator macrophage-inflammatory protein (MIP-1), eotaxin, as well as several other related chemokines. Mice lacking the chemokine receptor CCR1 have defects in neutrophil trafficking and proliferation.Synonyms: C-C CKR-1, C-C chemokine receptor type 1, CC-CKR-1, CCR-1, CMKBR1, CMKR1, HM145, LD78 receptor, MIP1 alpha Receptor, Macrophage inflammatory protein 1-alpha receptor, RANTES-R, SCYAR1

    基因ID

    1230

    NCBI登录号

    NP_001286

    UniProt

    P32246
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