RGS3 抗体 (AA 401-519)
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Quick Overview for RGS3 抗体 (AA 401-519) (ABIN127074)
抗原
See all RGS3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 401-519
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特异性
- This antibody detects human RGS3. Other species not tested.
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纯化方法
- Protein A chromatography
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免疫原
- E. coli-expressed human RGS3 (aa 401-519)
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应用备注
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Western Blot: 1.0 μg/mL. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.2 mg/mL
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缓冲液
- PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody undiluted (in aliquots) at -20 °C to -70 °C.
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- RGS3 (Regulator of G-Protein Signaling 3 (RGS3))
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别名
- RGS3
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背景
- RGS3 (regulator of G protein signaling 3) is a 519-residue protein that is widely expressed in many tissues and cells. The protein contains an RGS domain near the carboxy terminus that serves as a GTPase-activating protein (GAP). RGS3 negatively regulates the activation of Giα and Gαq. A truncated RGS3 (RGS3T), with its N-terminal 313 residues removed, has been shown to negatively regulate acenylyl cyclase and PLC. RGS3T may be localized in the nucleus and RGS3 is found in cytoplasm. Translocation to membrane is important for the RGS proteins to interact with heterotrimeric G proteins.Synonyms: RGP3, Regulator of G-protein signaling 3
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基因ID
- 5998
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NCBI登录号
- NP_060260
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UniProt
- P49796
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途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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