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FOXO4 抗体 (pSer193)

FOXO4 适用: 人, Hamster WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN127070
发货至: 中国
  • 抗原 See all FOXO4 抗体
    FOXO4 (Forkhead Box O4 (FOXO4))
    抗原表位
    • 20
    • 18
    • 15
    • 10
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer193
    适用
    • 134
    • 71
    • 62
    • 10
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    人, Hamster
    宿主
    • 132
    • 1
    • 1
    克隆类型
    • 124
    • 10
    多克隆
    标记
    • 62
    • 8
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    This FOXO4 antibody is un-conjugated
    应用范围
    • 103
    • 50
    • 39
    • 39
    • 24
    • 17
    • 16
    • 9
    • 7
    • 2
    • 1
    • 1
    Western Blotting (WB)
    特异性
    Phospho-AFX (Ser193) antibody detects only the phosphorylated Ser193 of AFX and does not react with nonphosphorylated AFX.
    纯化方法
    Peptide affinity chromatography
    Top Product
    Discover our top product FOXO4 Primary Antibody
  • 应用备注
    The antibody can be used for Western blotting (1-2 μg/mL).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 30 % glycerol, 0.5 % BSA, and 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store (in aliquots) at -20 °C. For long term storage freeze at -70 °C.
  • 抗原
    FOXO4 (Forkhead Box O4 (FOXO4))
    别名
    FOXO4 / AFX1 / MLLT7 (FOXO4 产品)
    别名
    FOXO4 antibody, foxo4 antibody, AFX antibody, AFX1 antibody, MLLT7 antibody, Afxh antibody, Mllt7 antibody, afx antibody, RGD1561201 antibody, forkhead box O4 antibody, forkhead box O4 L homeolog antibody, FOXO4 antibody, foxo4.L antibody, Foxo4 antibody
    背景
    The forkhead family of transcription factors is involved in tumorigenesis in rhabdomyosarcoma and acute leukemias. Within the family, three members (FKHR, AFX, AND FKHRL1) have sequence similarity to the nematode homolog Daf 16, recently shown to mediate signaling via a pathway involving IGFR1, P13-K and Akt. There are three potential Akt phosphorylation sites on the FKHR proteins. One site, FKHR Ser256 is found in the Forkhead domain and the other two are outside this domain. Recent studies show that phosphorylation of FKHR family members by Akt promotes cell survival. Phosphorylation regulates FKHR nuclear translocation and target gene transcription. Insulin also stimulates FKHR phosphorylation at Ser253.Synonyms: Fork head domain transcription factor AFX1, Forkhead box protein O4
    基因ID
    4303
    NCBI登录号
    NP_001164402
    UniProt
    P98177
    途径
    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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