电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

FOXO4 抗体 (pSer193)

This anti-FOXO4 antibody is a 兔 多克隆 antibody detecting FOXO4 in WB. Suitable for 人 和 Hamster.
产品编号 ABIN127070
发货至: 中国

Quick Overview for FOXO4 抗体 (pSer193) (ABIN127070)

抗原

See all FOXO4 抗体
FOXO4 (Forkhead Box O4 (FOXO4))

适用

  • 135
  • 71
  • 62
  • 10
  • 6
  • 6
  • 6
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
人, Hamster

宿主

  • 133
  • 1
  • 1

克隆类型

  • 122
  • 13
多克隆

标记

  • 64
  • 7
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
This FOXO4 antibody is un-conjugated

应用范围

  • 105
  • 49
  • 39
  • 39
  • 26
  • 18
  • 16
  • 9
  • 8
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 26
    • 18
    • 14
    • 10
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer193

    特异性

    Phospho-AFX (Ser193) antibody detects only the phosphorylated Ser193 of AFX and does not react with nonphosphorylated AFX.

    纯化方法

    Peptide affinity chromatography
  • 应用备注

    The antibody can be used for Western blotting (1-2 μg/mL).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS containing 30 % glycerol, 0.5 % BSA, and 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store (in aliquots) at -20 °C. For long term storage freeze at -70 °C.
  • 抗原

    FOXO4 (Forkhead Box O4 (FOXO4))

    别名

    FOXO4 / AFX1 / MLLT7

    背景

    The forkhead family of transcription factors is involved in tumorigenesis in rhabdomyosarcoma and acute leukemias. Within the family, three members (FKHR, AFX, AND FKHRL1) have sequence similarity to the nematode homolog Daf 16, recently shown to mediate signaling via a pathway involving IGFR1, P13-K and Akt. There are three potential Akt phosphorylation sites on the FKHR proteins. One site, FKHR Ser256 is found in the Forkhead domain and the other two are outside this domain. Recent studies show that phosphorylation of FKHR family members by Akt promotes cell survival. Phosphorylation regulates FKHR nuclear translocation and target gene transcription. Insulin also stimulates FKHR phosphorylation at Ser253.Synonyms: Fork head domain transcription factor AFX1, Forkhead box protein O4

    基因ID

    4303

    NCBI登录号

    NP_001164402

    UniProt

    P98177

    途径

    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
You are here:
Chat with us!