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Cathepsin L 抗体

The 兔 多克隆 anti-Cathepsin L antibody is suitable to detect Cathepsin L in samples from 人, 小鼠 和 大鼠. It has been validated for WB.
产品编号 ABIN127049
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Cathepsin L 抗体 (ABIN127049)

抗原

See all Cathepsin L (CTSL1) 抗体
Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

适用

  • 72
  • 39
  • 36
  • 21
  • 6
  • 4
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 90
  • 18
  • 2

克隆类型

  • 90
  • 20
多克隆

标记

  • 57
  • 17
  • 8
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Cathepsin L antibody is un-conjugated

应用范围

  • 82
  • 36
  • 32
  • 13
  • 13
  • 13
  • 12
  • 10
  • 7
  • 5
  • 5
  • 5
  • 1
Western Blotting (WB)
  • 特异性

    Detects both the proenzyme and the mature form of cathepsin L.

    纯化方法

    Affinity purified

    免疫原

    Synthetic peptide surrounding amino acid 223 of human Cathepsin L
  • 应用备注

    Western Blot: 0.5-4 μg/mL, Jurkat cell lysate can be used as a positive control.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % thimerosal.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C/-80 °C

    储存方法

    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -20 °C to -70 °C.
  • 抗原

    Cathepsin L (CTSL1) (Cathepsin L1 (CTSL1))

    别名

    Cathepsin L1

    背景

    Cathepsin L is a normal lysosomal cysteine endoproteases that is expressed in all cells. The latent 39 kDa pro-Cathepsin L must be processed by cleavage of the 96 amino acid propeptide, to generate the active two-chain form made up of 21 and 5 kDa subunits. Mature Cathepsin L is normally localized in the lysosomes where it plays a major role in intracellular protein catabolism. The fact that Cathepsin L is also capable of degrading extracellular matrix proteins suggests that it may play a role in invation and metastasis and could be a useful prognostic indicator for cancer.Synonyms: CTSL, CTSL1, Cathepsin-L1, MEP, Major excreted protein

    基因ID

    1514

    NCBI登录号

    NP_001903

    UniProt

    P07711

    途径

    Activation of Innate immune Response, Toll-Like Receptors Cascades
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