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HSP70 抗体

This 兔 多克隆 antibody specifically detects HSP70 in WB. It exhibits reactivity toward 人, Cow, Pig, 猴 和 Hamster.
产品编号 ABIN127006
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for HSP70 抗体 (ABIN127006)

抗原

See all HSP70 抗体
HSP70 (Heat Shock Protein 70 (HSP70))

适用

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人, Cow, Pig, 猴, Hamster

宿主

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克隆类型

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多克隆

标记

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This HSP70 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 特异性

    The antibody is specific for the inducible form of Hsp70 (Hsp72) and does not cross-react with the constitutive Hsc70 (Hsc73).

    纯化方法

    Affinity purified
  • 应用备注

    Western Blot: 1-2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    PBS, pH 7.2, containing 50 % glycerol, 1 % BSA, 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C/-80 °C

    储存方法

    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
  • 抗原

    HSP70 (Heat Shock Protein 70 (HSP70))

    别名

    Heat Shock Protein 70 / HSP70

    背景

    Hsp70, one class of stress proteins, is comprised of multiple members, all of which bind ATP in vitro, but are localized within different intracellular compartments. These include: a) the constitutive Hsc70 (or cognate) present within the cytosol/nucleus, b) the highly stress-inducible Hsp70 present within the cytosol/ nucleus/nucleolus, c) the constitutive glucose regulated 78 kDa (or BiP) protein present within the lumen of the endoplasmic reticulum, and d) the glucose regulated 75 kDa protein present within the mitochondria. Hsp70 is typically not expressed in the cell under normal growth conditions, but is expressed at high levels in the cell experiencing stress. Consequently, detection of Hsp70 using an antibody specific for the inducible form is quite useful in ascertaining whether a stress response has occurred in the cell. It should be noted, however, that there is a constitutive level of Hsp70 expression in some cell types such as primates, e.g., human and monkey. Nevertheless increased expression of Hsp70 is observed in such cells following stress.Synonyms: HSP70-1/HSP70-2, HSP70.1, HSPA1, HSPA1A, HSPA1B, Heat shock 70 kDa protein 1A/1B

    基因ID

    3303

    NCBI登录号

    NP_005336

    UniProt

    P08107
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