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Calreticulin 抗体 (C-Term)

CALR 适用: 人, 小鼠, 大鼠, 猴 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN126998
发货至: 中国
  • 抗原 See all Calreticulin (CALR) 抗体
    Calreticulin (CALR)
    抗原表位
    • 16
    • 12
    • 7
    • 6
    • 6
    • 4
    • 4
    • 3
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    • 2
    • 2
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    • 1
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    C-Term
    适用
    • 117
    • 60
    • 48
    • 9
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    • 1
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    人, 小鼠, 大鼠, 猴
    宿主
    • 112
    • 8
    • 2
    • 1
    克隆类型
    • 106
    • 17
    多克隆
    标记
    • 63
    • 12
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    • 7
    • 5
    • 3
    • 1
    • 1
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    This Calreticulin antibody is un-conjugated
    应用范围
    • 99
    • 52
    • 45
    • 36
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    • 15
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    • 13
    • 3
    • 2
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    Recognizes a 60 kDa calreticulin on SDS-PAGE immunoblots.
    纯化方法
    Protein A purified
    免疫原
    Synthetic peptide from the C-terminus of Human Calreticulin
    Top Product
    Discover our top product CALR Primary Antibody
  • 应用备注
    Western blot: 0.5-2 μg/mL. Immunohistochemistry. NIH/3T3 cell lysate can be used as a positive control.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    PBS containing 1 mg/mL BSA, 1.5 mM sodium azide and 50 % glycerol
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C/-80 °C
    储存方法
    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
  • 抗原
    Calreticulin (CALR)
    别名
    Calreticulin (CALR 产品)
    别名
    CRT antibody, RO antibody, SSA antibody, cC1qR antibody, crc antibody, crt antibody, Calregulin antibody, CG9429 antibody, Clr antibody, Dmel\\CG9429 antibody, anon-EST:Liang-2.11 antibody, anon-EST:Liang-2.17 antibody, anon-EST:fe3D7 antibody, clone 2.11 antibody, clone 2.17 antibody, eth antibody, potp antibody, cc1qr antibody, ssa antibody, NV19007 antibody, CRP55 antibody, ERp60 antibody, HACBP antibody, CHOT1 antibody, CHT1 antibody, CT1 antibody, AA589632 antibody, CRTR antibody, Creat antibody, CCDS1 antibody, calrl2 antibody, fc66d10 antibody, wu:fc66d10 antibody, wu:fj50c03 antibody, zgc:66153 antibody, calreticulin antibody, calreticulin L homeolog antibody, Calreticulin antibody, putative calreticulin antibody, solute carrier family 6 member 8 antibody, solute carrier family 6 (neurotransmitter transporter, creatine), member 8 antibody, CALR antibody, calr.L antibody, Crt antibody, crt antibody, CRT antibody, Calr antibody, calr antibody, LMJF_31_2600 antibody, Crc antibody, Slc6a8 antibody, SLC6A8 antibody, LOC8269812 antibody
    背景
    Calreticulin is a calcium binding protein found in abundance in the endoplasmic reticulum and the sarcoplasmic reticulum. Like many other ER proteins, it has the conserved ER retention KDEL (Lys-Asp-Glu-Leu) sequence at its C-terminus. Calreticulin has also been detected in the nucleus and nuclear envelop. Recent studies suggest that this soluble ER protein has a multifunctional role as it appears to be involved in calcium storage and regulation as well as having a molecular chaperone activity. Studies also suggest its involvement in certain autoimmune diseases. Consistence with its multiple functions the calreticulin molecule appears to have a zonal character. The protein has both high and low affinity calcium binding sites.Synonyms: CALR, CRP55, CRTC, Calregulin, ERp60, HACBP, grp60
    基因ID
    811
    NCBI登录号
    NP_004334
    UniProt
    P27797
    途径
    Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response
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