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Calreticulin 抗体

The 小鼠 单克隆 anti-Calreticulin antibody (Clone S75) (ABIN126927) specifically detects Calreticulin in WB, IP 和 IHC (p). The antibody is reactive with 人 和 猴 samples.
产品编号 ABIN126927
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Calreticulin 抗体 (ABIN126927)

抗原

See all Calreticulin (CALR) 抗体
Calreticulin (CALR)

适用

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人, 猴

宿主

  • 143
  • 21
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小鼠

克隆类型

  • 122
  • 46
单克隆

标记

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This Calreticulin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

S75
  • 特异性

    The antibody recognizes a 63 kDa Calreticulin on SDS-PAGE Immunoblots.

    产品特性

    Synonyms: CRP55, Calregulin, HACBP, ERp60, grp60, CALR, CRTC

    纯化方法

    Affinity Chromatography on Protein A

    免疫原

    Calreticulin-maltose binding fusion protein

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.2 mg/mL

    缓冲液

    PBS containing 1 mg/mL BSA, 0.02 % Thimerosal and 50 % Glycerol

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store the antibody at -20 °C or For long term storage, aliquot and refreeze at -70 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    Calreticulin (CALR)

    别名

    Calreticulin

    背景

    Calreticulin is a calcium binding protein found in abundance in the endoplasmic reticulum and the sarcoplasmic reticulum. Like many other ER proteins, it has the conserved ER retention KDEL (Lys-Asp-Glu-Leu) sequence at its C-terminus. Calreticulin has also been detected in the nucleus and nuclear envelop. Recent studies suggest that this soluble ER protein has a multifunctional role as it appears to be involved in calcium storage and regulation as well as having a molecular chaperone activity. Studies also suggest its involvement in certain autoimmune diseases. Consistence with its multiple functions the calreticulin molecule appears to have a zonal character. The protein has both high and low affinity calcium binding sites.Synonyms: CALR, CRP55, CRTC, Calregulin, ERp60, HACBP, grp60

    基因ID

    811

    UniProt

    P27797

    途径

    Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, ER-Nucleus Signaling, Unfolded Protein Response
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