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VASP 抗体 (pSer157) (FITC)

Name: VASP 抗体 (pSer157) (FITC)
SKU: ABIN126907
Availability: OutOfStock

VASP 适用: 人, 小鼠 IF, FACS 宿主: 小鼠 Monoclonal 5C6 FITC

(1 reference)

产品编号 ABIN126907

发货至: 中国

Datasheet as PDF

抗原 See all VASP 抗体

VASP (Vasodilator-Stimulated phosphoprotein (VASP))
抗原表位
18

17

15

10

9

8

6

5

4

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer157
适用
134

64

58

11

10

9

5

2

2

2

1

1
人, 小鼠
宿主
115

18

2
小鼠
Compatible Secondaries
克隆类型
111

24
单克隆
标记
78

10

5

5

5

5

5

5

5

3

2

2

1

1

1

1

1
This VASP antibody is conjugated to FITC
应用范围
103

51

48

25

22

16

14

14

11

11

5

5

4

1
Immunofluorescence (IF), Flow Cytometry (FACS)

特异性

This antibody recognizes VASP only, when Ser157 is phosphorylated, a site preferred by cAMP-dependent protein kinase (PKA). The antibody does not crossreact with the non-phosphorylated form of VASP nor with unrelated serine-phosphorylated proteins. Therefore, this antibody is able to monitor the phosphorylation state of VASP Serine157 as well as PKA activity.

产品特性

Synonyms: Vasodilator-stimulated phosphoprotein

纯化方法

Subsequent Thiophilic Adsorption and Size Exclusion Chromatography.

免疫原

Phosphopeptide conjugated to KLH. Epitope: Phosphoserine 157AA Sequence: R-R-V-pS-N-A-G

克隆位点

5C6

亚型

IgG1

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anti-Vasodilator-Stimulated phosphoprotein (VASP) antibody
VASP 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated

anti-Vasodilator-Stimulated phosphoprotein (VASP) (AA 1-100) antibody
VASP 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Vasodilator-Stimulated phosphoprotein (VASP) (pSer157) antibody
VASP 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated

anti-Vasodilator-Stimulated phosphoprotein (VASP) (pSer157) antibody
VASP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Vasodilator-Stimulated phosphoprotein (VASP) (pSer239) antibody
VASP 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Vasodilator-Stimulated phosphoprotein (VASP) (AA 1-380) antibody
VASP 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Vasodilator-Stimulated phosphoprotein (VASP) (pSer239) antibody
VASP 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Vasodilator-Stimulated phosphoprotein (VASP) antibody
VASP 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Vasodilator-Stimulated phosphoprotein (VASP) (pSer157) antibody
VASP 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

Flow Cytometry. Immunocytochemistry: 1-10 μg/mL (may tolerate 0.5 % Formaldehyde fixation). For Immunoblotting and Immunoprecipitation use ABIN126908 and ABIN126905.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
浓度

0.5 mg/mL

缓冲液

2 x PBS containing 0.09 % Sodium Azide, PEG and Sucrose

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C

储存方法

Aliquote and freeze (in liquid nitrogen at -20 °C to -80 °C). Thaw aliquots at 37 °C. Thawed aliquots may be stored at 2-8 °C up to 3 months. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

有效期

12 months
Iyú, Glenn, White, Fox, Heptinstall: "Adenosine derived from ADP can contribute to inhibition of platelet aggregation in the presence of a P2Y12 antagonist." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 31, Issue 2, pp. 416-22, (2011) (PubMed).
抗原

VASP (Vasodilator-Stimulated phosphoprotein (VASP))

别名

VASP (VASP 产品)

别名

vasp antibody, MGC80889 antibody, wu:fb23b04 antibody, wu:fk84g05 antibody, zgc:110347 antibody, si:dkey-113g17.1 antibody, si:ch211-202c21.1 antibody, DDBDRAFT_0188463 antibody, DDBDRAFT_0229340 antibody, DDB_0188463 antibody, DDB_0229340 antibody, VASP antibody, vasodilator stimulated phosphoprotein S homeolog antibody, vasodilator stimulated phosphoprotein b antibody, protein enabled antibody, vasodilator-stimulated phosphoprotein antibody, vasodilator stimulated phosphoprotein a antibody, vasodilator stimulated phosphoprotein antibody, vasp.S antibody, vaspb antibody, LOC5573842 antibody, CpipJ_CPIJ004706 antibody, CpipJ_CPIJ004707 antibody, vasP antibody, vasp antibody, VASP antibody, vaspa antibody, Vasp antibody

背景

VASP (vasodilator stimulated phosphoprotein) plays an important role in ANF / NO / cGMP Protein kinase and cAMP / cAMP Protein kinase signalling pathways. VASP is expressed in almost all human and animal cell lines, particularly high concentrations are found in thrombocytes, vascular smooth muscle cells and fibroblasts. In cultured cells VASP is associated with focal contacts, cell-cell-contacts, microfilaments and dynamic membrane regions such as the leading edge. In vitro binding data show that VASP binds to profilin, zyxin, vinculin, and the Listeria spp. surface protein ActA. Functional evidence indicates that VASP is a crucial factor involved in the enhancement of actin filament formation.Synonyms: Vasodilator-stimulated phosphoprotein

分子量

46/50 kDa

基因ID

7408

UniProt

P50552

途径

TCR Signaling, Regulation of Actin Filament Polymerization, Tube Formation