BCL10 抗体 (pSer138)
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北京 101111
Quick Overview for BCL10 抗体 (pSer138) (ABIN126733)
抗原
See all BCL10 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pSer138
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特异性
- This antibody specifically recognizes bcl-10 phosphorylated at Serine 138 at 32 kDa in Western blot.
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产品特性
- Synonyms: BCL10, CIPER, CLAP, cCARMEN, mE10, c-E10, hCLAP, B-cell CLL/lymphoma 10, CED-3/ICH-1prodomain homologous E10-like regulator, CARD-containing molecule enhancingNF-kappa-B, Cellular homolog of vCARMEN, Mammalian CARD-containing adapter moleculeE10, Cellular-E10, CARD-like apoptotic protein
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纯化方法
- Subsequent Thiophilic Adsorption and Size Exclusion Chromatography.
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组件
- incl. positive Control
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免疫原
- Phosphopeptide conjugated to KLH
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亚型
- IgG1
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应用备注
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Western Blot: 0.5 μg/mL for HRPO/ECL detection. Recommended blocking buffer: BSA/Tween 20 based blocking and blot incubation buffer. Included Positive Control: Cell lysate from serum starved SW480 cells (please see: 'Protocols').
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
实验流程
- Positive Control Cell Lysate: SW 480 Untreated
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限制
- 仅限研究用
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溶解方式
- Restore with 1 mL water (15 min, RT).
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缓冲液
- 1 mL2 x PBS / 0.09 % Sodium Azide / PEG and Sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C/-80 °C
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储存方法
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Store lyophilized (preferably in a desiccator) at -20 °C and reconstituted (aliquote andfreeze in liquid nitrogen) at -80 °C. Thaw aliquots at 37 °C. Thawed aliquots may be stored at 4 °C up to 3 months. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
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别名
- Bcl-10
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背景
- Bcl-10 is an apoptosis-inducing molecule interacting with caspase 9. Bcl-10 enhances pro-caspase 9 processing and induces apoptosis through caspase 9 activation.Synonyms: B-cell CLL/lymphoma 10, BCL10, CARD-containing molecule enhancing NF-kappa-B, CARD-like apoptotic protein, CED-3/ICH-1 prodomain homologous E10-like regulator, CIPER, CLAP, Cellular homolog of vCARMEN, Cellular-E10, Mammalian CARD-containing adapter molecule E10, c-E10, cCARMEN, hCLAP, mE10
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基因ID
- 8915
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UniProt
- O95999
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
抗原
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