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CXCR6 抗体 (AA 11-25)

CXCR6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN126328
发货至: 中国
  • 抗原 See all CXCR6 抗体
    CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))
    抗原表位
    • 9
    • 8
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 11-25
    适用
    • 48
    • 11
    • 8
    • 5
    • 3
    • 3
    • 1
    宿主
    • 46
    • 2
    • 1
    • 1
    克隆类型
    • 47
    • 3
    多克隆
    标记
    • 31
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CXCR6 antibody is un-conjugated
    应用范围
    • 38
    • 22
    • 9
    • 9
    • 4
    • 4
    • 2
    • 2
    Western Blotting (WB)
    特异性
    SP1286P recognises the orphan G protein-coupled chemokine receptor CXCR6, also known as CDw186. CXCR6 has been identified as a co-receptor for simian immunodeficiency virus (SIV), HIV-2 and HIV-1. Lymphoid tissues and activated peripheral blood lymphocytes express CXCR6 mRNA.
    纯化方法
    Affinity purified immunoglobulin fraction
    免疫原
    Peptide corresponding to aa 11 to 25 of human CXCR6/CDw186 (NT)
    亚型
    IgG
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  • 应用备注
    Western blot (1/500).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C or at -20 °C if preferred. Avoid repeated freezing and thawing.
    Shelf Life: One year from despatch.
    有效期
    12 months
  • 抗原
    CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))
    别名
    CD186 / CXCR6 (CXCR6 产品)
    别名
    BONZO antibody, CD186 antibody, STRL33 antibody, TYMSTR antibody, BB217514 antibody, C-X-C motif chemokine receptor 6 antibody, chemokine (C-X-C motif) receptor 6 L homeolog antibody, chemokine (C-X-C motif) receptor 6 antibody, CXCR6 antibody, cxcr6.L antibody, Cxcr6 antibody
    背景
    Human Immunodeficiency Virus (HIV) and Simian Immunodeficiency Virus (SIV) require coreceptors to enter and infect target cells. They are dependent upon an interaction between the viral envelope glycoprotein with T cell antigen T4 (CD4) and a G protein coupled receptor (GPCR). HIV1 infection relies upon interaction with a chemokine receptor, usually chemokine (C-C) receptor 5 (CCR5). During progression of the infection, the virus tends to rely upon chemokine (C-X-C) receptor 4 (CXCR4). SIV also utilizes CCR5 in the early stages of infection, but during progression it tends to rely on two orphan GPCR's named chemokine (C-X-C) receptor 6 (Bonzo) and G protein coupled receptor 15 (BOB/GRP15). Bonzo mRNA expression has been localized to lymphoid tissues and activated peripheral blood lymphocytes.Synonyms: BONZO, CDw186, CXC-R6, CXCR-6, G-protein coupled receptor STRL33, G-protein coupled receptor bonzo, STRL33, TYMSTR
    基因ID
    10663
    UniProt
    O00574
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