CXCR6 抗体 (AA 11-25)
Quick Overview for CXCR6 抗体 (AA 11-25) (ABIN126328)
抗原
See all CXCR6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 11-25
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特异性
- SP1286P recognises the orphan G protein-coupled chemokine receptor CXCR6, also known as CDw186. CXCR6 has been identified as a co-receptor for simian immunodeficiency virus (SIV), HIV-2 and HIV-1. Lymphoid tissues and activated peripheral blood lymphocytes express CXCR6 mRNA.
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纯化方法
- Affinity purified immunoglobulin fraction
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免疫原
- Peptide corresponding to aa 11 to 25 of human CXCR6/CDw186 (NT)
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亚型
- IgG
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anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (Cytoplasmic Domain) antibody
CXCR6 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (C-Term) antibodyCXCR6 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (C-Term) antibodyVerified CXCR6 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) antibodyCXCR6 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (C-Term) antibodyCXCR6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (AA 1-342) antibodyCXCR6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (AA 319-338) antibodyCXCR6 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (N-Term) antibodyCXCR6 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot (1/500).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store undiluted at 2-8 °C or at -20 °C if preferred. Avoid repeated freezing and thawing.
Shelf Life: One year from despatch. -
有效期
- 12 months
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- CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))
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别名
- CD186 / CXCR6
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背景
- Human Immunodeficiency Virus (HIV) and Simian Immunodeficiency Virus (SIV) require coreceptors to enter and infect target cells. They are dependent upon an interaction between the viral envelope glycoprotein with T cell antigen T4 (CD4) and a G protein coupled receptor (GPCR). HIV1 infection relies upon interaction with a chemokine receptor, usually chemokine (C-C) receptor 5 (CCR5). During progression of the infection, the virus tends to rely upon chemokine (C-X-C) receptor 4 (CXCR4). SIV also utilizes CCR5 in the early stages of infection, but during progression it tends to rely on two orphan GPCR's named chemokine (C-X-C) receptor 6 (Bonzo) and G protein coupled receptor 15 (BOB/GRP15). Bonzo mRNA expression has been localized to lymphoid tissues and activated peripheral blood lymphocytes.Synonyms: BONZO, CDw186, CXC-R6, CXCR-6, G-protein coupled receptor STRL33, G-protein coupled receptor bonzo, STRL33, TYMSTR
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基因ID
- 10663
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UniProt
- O00574
抗原
-
