LAT2 抗体 (Cytoplasmic Domain)
(1 reference)Quick Overview for LAT2 抗体 (Cytoplasmic Domain) (ABIN125754)
抗原
See all LAT2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 124-203, Cytoplasmic Domain
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原理
- Anti-NTAL Purified
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特异性
- The polyclonal antibody recognizes N-terminal cytoplasmic domain of mouse Non-T cell Activation Linker (NTAL), also known as LAB (linker of activated B cells), a 25 kDa transmembrane adaptor protein present in membrane microdomains (rafts) of B cells, NK cells and myeloid cells.
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无交叉反应
- 人
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交叉反应 （详细）
- Mouse, Other species Not tested
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纯化方法
- Purified by ligand affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- Recombinant N-terminal cytoplasmic domain (aa 124-203) of mouse NTAL.
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anti-Linker For Activation of T Cells Family, Member 2 (LAT2) (AA 91-243), (Cytoplasmic Domain) antibody
LAT2 适用: 人, 小鼠 WB, IP, ICC, ICFC 宿主: 小鼠 Monoclonal NAP-07 unconjugated
anti-Linker For Activation of T Cells Family, Member 2 (LAT2) (AA 30-209) antibodyLAT2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Linker For Activation of T Cells Family, Member 2 (LAT2) antibodyLAT2 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Linker For Activation of T Cells Family, Member 2 (LAT2) (AA 91-243), (Cytoplasmic Domain) antibody (PE)LAT2 适用: 人, 小鼠 ICFC 宿主: 小鼠 Monoclonal NAP-07 PE
anti-Linker For Activation of T Cells Family, Member 2 (LAT2) (AA 32-192) antibodyLAT2 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Linker For Activation of T Cells Family, Member 2 (LAT2) (AA 1-20) antibodyLAT2 适用: 人 IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Linker For Activation of T Cells Family, Member 2 (LAT2) antibodyLAT2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Linker For Activation of T Cells Family, Member 2 (LAT2) (C-Term) antibodyLAT2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Linker For Activation of T Cells Family, Member 2 (LAT2) (AA 91-244) antibodyLAT2 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal NAP-07 unconjugated
anti-Linker For Activation of T Cells Family, Member 2 (LAT2) (Internal Region) antibodyVerified LAT2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
- Western blotting: Recommended dilution: 1 μg/mL, positive control: murine spleen, non-reducing conditions.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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: "Negative regulation of mast cell signaling and function by the adaptor LAB/NTAL." in: The Journal of experimental medicine, Vol. 200, Issue 8, pp. 1001-13, (2004) (PubMed).
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: "Negative regulation of mast cell signaling and function by the adaptor LAB/NTAL." in: The Journal of experimental medicine, Vol. 200, Issue 8, pp. 1001-13, (2004) (PubMed).
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- LAT2 (Linker For Activation of T Cells Family, Member 2 (LAT2))
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别名
- NTAL
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背景
- Linker for activation of T cells family member 2,NTAL (non-T cell activation linker), also known as LAB (linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells and macrophages. It is a negative regulator of early stages of BCR-dependent B cell signaling and serves as a negative regulator also in mast cells. However, in mast cells, NTAL also contributes to some activation processes, partially overlapping with LAT function.,LAB, LAT2
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基因ID
- 7462
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UniProt
- Q9GZY6
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途径
- Fc-epsilon Receptor Signaling Pathway, BCR Signaling
抗原
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