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CD9 抗体

CD9 适用: 人 FACS, WB, IHC (p), Func, CyTOF 宿主: 小鼠 Monoclonal MEM-61 unconjugated
产品编号 ABIN125680
发货至: 中国
  • 抗原 See all CD9 抗体
    CD9
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD9 antibody is un-conjugated
    应用范围
    • 114
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    Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Functional Studies (Func), Cytometry by Time of Flight (CyTOF)
    特异性
    The antibody MEM-61 recognizes an epitope on second extracellular domain (EC2) of CD9 antigen, a 24 kDa transmembrane protein expressed on platelets, monocytes, pre-B lymphocytes, granulocytes and activated T lymphocytes.
    交叉反应 (详细)
    Human
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Pre-B cell line NALM-6.
    克隆位点
    MEM-61
    亚型
    IgG1
    Top Product
    Discover our top product CD9 Primary Antibody
  • 应用备注
    Functional application: The antibody MEM-61 induces FcγR-dependent platelet aggregation.
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Western blotting: Recommended dilution: 2-4 μg/mL, non-reducing conditions.
    Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/mL, positive tissue: prostate.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4
    储存液
    Azide free
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • Singh, Sugimoto, Dhawan, Harris: "Juxtacrine activation of EGFR regulates claudin expression and increases transepithelial resistance." in: American journal of physiology. Cell physiology, Vol. 293, Issue 5, pp. C1660-8, (2007) (PubMed).

    Stöckl, Majdic, Fischer, Maurer, Knapp: "Monomorphic molecules function as additional recognition structures on haptenated target cells for HLA-A1-restricted, hapten-specific CTL." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 5, pp. 2724-33, (2001) (PubMed).

  • 抗原
    CD9
    别名
    CD9 (CD9 产品)
    背景
    CD9 Molecule,CD9 belongs to proteins of tetraspanin family that orchestrate cholesterol-associated tetraspanin-enriched signaling microdomains within the plasma membrane, forming complexes with each other as well as with integrins, membrane-anchored growth factors and other proteins. CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion, plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on the dendritic cell plasma membrane which is important for effective T cell stimulation. CD9 is also considered as metastasis suppressor in solid tumors.,MIC3, MRP-1, BTCC-1, DRAP-27, TSPAN29, BA2
    基因ID
    928
    UniProt
    P21926
    途径
    Response to Water Deprivation, Cell-Cell Junction Organization
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