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Cytokeratin 19 抗体 (Biotin)

There are 3+ publications for this product available. The 小鼠 单克隆 anti-Cytokeratin 19 antibody is suitable to detect Cytokeratin 19 in samples from 人. It has been validated for WB, FACS, IHC (p), ICC 和 IP.
产品编号 ABIN125675
发货至: 中国
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Quick Overview for Cytokeratin 19 抗体 (Biotin) (ABIN125675)

抗原

See all Cytokeratin 19 (KRT19) 抗体
Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))

适用

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小鼠

克隆类型

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单克隆

标记

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This Cytokeratin 19 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunoprecipitation (IP)

克隆位点

BA-17
  • 原理

    Anti-Cytokeratin 19 Biotin

    交叉反应 (详细)

    Human

    产品特性

    The antibody BA-17 reacts with cytokeratin 19 (40 kDa intracellular antigen) in human tissue. Cytokeratin 19 is not expressed in hepatocytes, it is often co-expressed with cytokeratin 7.

    纯化方法

    Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.

    免疫原

    Mammary organoids.

    亚型

    IgG1, kappa
  • 应用备注

    Western blotting: Recommended dilution: 1-2 μg/mL.
    Flow cytometry: Recommended dilution: 4-10 μg/mL. Intracellular staining.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • Lewis, Klimstra, Varmus: "The c-myc and PyMT oncogenes induce different tumor types in a somatic mouse model for pancreatic cancer." in: Genes & development, Vol. 17, Issue 24, pp. 3127-38, (2003) (PubMed).

    Bartek, Durban, Hallowes, Taylor-Papadimitriou: "A subclass of luminal epithelial cells in the human mammary gland, defined by antibodies to cytokeratins." in: Journal of cell science, Vol. 75, pp. 17-33, (1985) (PubMed).

    Bartek, Taylor-Papadimitriou, Miller, Millis: "Patterns of expression of keratin 19 as detected with monoclonal antibodies in human breast tissues and tumours." in: International journal of cancer. Journal international du cancer, Vol. 36, Issue 3, pp. 299-306, (1985) (PubMed).

  • 抗原

    Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))

    别名

    Cytokeratin 19

    背景

    Keratin 19,Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. They are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.,K19, CK19, CYK19, KRT19, K1CS

    基因ID

    3880

    UniProt

    P08727
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