TACR1 抗体 (C-Term)
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Quick Overview for TACR1 抗体 (C-Term) (ABIN122523)
抗原
See all TACR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects Tachykinin receptor 1 (TACR1) at C-term. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except DTNB (44 %).
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交叉反应 (详细)
- Species reactivity (tested):Human
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纯化方法
- Immunoaffinity chromatography.
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免疫原
- Synthetic peptide - KLH conjugated
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应用备注
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Immunohistochemistry with formalin fixed paraffin embedded tissues: 1-40 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.09 % Sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-80 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- TACR1 (Tachykinin Receptor 1 (TACR1))
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背景
- Tachykinin receptor 1, a member of the tachykinin receptor subfamily, is involved in the mediation of phosphatidylinositol metabolism by the tachykinin substance P, also referred to as neurokinin 1. It is associated with the management of depression, anxiety, and stress. It is also involved in regulating behavioral responses, neuronal survival, and cardiovascular and respiratory functions. The tachykinin receptor 1 is implicated in the progression of rheumatoid arthritis and osteoarthritis. Two variants of the tachykinin receptor 1 are produced by alternative splicing. Tachykinin receptor 1 has been reported primarily in brain, and in blood lymphocytes, nose, small intestine, and stomach. ESTs have been isolated from brain and spleen libraries.Synonyms: NK-1 receptor, NK-1R, NK1R, SPR, Substance-P receptor, TAC1R
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基因ID
- 6869
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UniProt
- P25103
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途径
- Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration
抗原
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