DRD4 抗体 (C-Term)
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北京 101111
Quick Overview for DRD4 抗体 (C-Term) (ABIN122473)
抗原
See all DRD4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Detects Dopamine Receptor D4 (family: GPCR, subfamily: Dopamine)
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纯化方法
- Peptide immunogen affinity column
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免疫原
- Synthetic peptide - KLH conjugated
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anti-Dopamine Receptor D4 (DRD4) (AA 365-391) antibody
DRD4 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB22909 unconjugated
anti-Dopamine Receptor D4 (DRD4) (C-Term) antibodyDRD4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D4 (DRD4) (AA 100-200) antibodyDRD4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D4 (DRD4) (C-Term) antibodyDRD4 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D4 (DRD4) (AA 365-391) antibodyDRD4 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 625CT1-5-4 unconjugated
anti-Dopamine Receptor D4 (DRD4) (C-Term) antibodyDRD4 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D4 (DRD4) (C-Term) antibodyDRD4 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D4 (DRD4) antibodyDRD4 适用: 人, 小鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D4 (DRD4) (AA 355-404) antibodyDRD4 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry on paraffin embedded sections: 10 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International. -
限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.7, containing 0.01 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-80 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- DRD4 (Dopamine Receptor D4 (DRD4))
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别名
- Dopamine D4 Receptor
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背景
- Dopamine Receptor D4 (DRD4), a Dopamine Receptor, has been suggested to affect personality, substance dependence, cognition, and emotion. DRD4 binds the antipsychotic medications clozapine and spiperone. DRD4 knock-out mice are anatomically normal but display altered locomotion and sensitivity to drugs such as clozapine, cocaine, and others. The DRD4 gene contains extensive polymorphisms consisting of variable numbers of tandem repeats (VNTR) in sequences corresponding to the third cytoplasmic loop of the receptor, at least 27 different haplotypes encoding 20 different protein variants have been documented. The frequency of the different variants varies among population groups. Studies have suggested a link between VNTR and human personality traits (such as novelty seeking) and diseases (such as schizophrenia, bipolar affective disorder, and Tourette syndrome), however, considerable debates exist regarding the validity and significance of such associations. DRD4 expression has been reported in various regions of the brain as well as in adrenal gland, artery, eye, heart, kidney, placenta, spinal cord, testis, and vas deferens. ESTs have been isolated from a kidney library.Synonyms: D(2C) dopamine receptor, D(4) dopamine receptor, DRD4
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基因ID
- 1815
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UniProt
- P21917
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途径
- cAMP Metabolic Process, Synaptic Membrane, Proton Transport, Photoperiodism, Negative Regulation of Transporter Activity
抗原
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