GHRHR 抗体 (C-Term)
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Quick Overview for GHRHR 抗体 (C-Term) (ABIN122454)
抗原
See all GHRHR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Reacts with Growth Hormone Releasing Hormone Receptor (family: GPCR, subfamily: Growth hormone releasing hormone)
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纯化方法
- Peptide Immunogen Affinity Chromatography.
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免疫原
- Synthetic peptide - KLH conjugated
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应用备注
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Immunohistochemistry with formalin fixed paraffin embedded tissues: 16 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.7, containing 0.01 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C forlonger. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- GHRHR (Growth Hormone Releasing Hormone Receptor (GHRHR))
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别名
- GHRH Receptor
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背景
- GHRHR, a Growth Hormone-Releasing Hormone Receptor, is involved in the proliferation and differentiation of somatotrophic pituitary cells and in disease. The GHRH receptor stimulates growth hormone (GH) secretion and synthesis in the pituitary. Mutations in this receptor cause either growth-hormone deficiency, resulting in dwarfism, or excessive production of the hormone, leading to gigantism. Four alternative splice variants have been identified that are tissue specific. GHRHR has been reported to be expressed primarily in the brain. ESTs have been isolated from brain and pituitary libraries.Synonyms: GHRHR, GRF receptor, GRFR, Growth hormone-releasing factor receptor, Growth hormone-releasing hormone receptor
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基因ID
- 2692
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UniProt
- Q02643
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Hormone Transport, Regulation of Intracellular Steroid Hormone Receptor Signaling, cAMP Metabolic Process
抗原
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