TNIK 抗体
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北京 101111
Quick Overview for TNIK 抗体 (ABIN122435)
抗原
See all TNIK 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Reacts with Traf2 and NCK-Interacting Kinase (TNIK) (Family: Protein Kinase, Subfamily: MSN)
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交叉反应 （详细）
- Species reactivity (expected):Mouse, RatSpecies reactivity (tested):Human
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纯化方法
- Peptide immunogen affinity column
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免疫原
- Synthetic peptide - KLH conjugated
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anti-TRAF2 and NCK Interacting Kinase (TNIK) (AA 1-110) antibody
TNIK 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2D2 unconjugated
anti-TRAF2 and NCK Interacting Kinase (TNIK) (AA 1-110) antibodyTNIK 适用: 人 ELISA, WB, RNAi 宿主: 小鼠 Monoclonal 1E4 unconjugated
anti-TRAF2 and NCK Interacting Kinase (TNIK) (AA 1-110) antibodyTNIK 适用: 人 ELISA, WB, IP 宿主: 小鼠 Monoclonal 4E4 unconjugated
anti-TRAF2 and NCK Interacting Kinase (TNIK) (Ser764) antibodyTNIK 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB59089 unconjugated
anti-TRAF2 and NCK Interacting Kinase (TNIK) (AA 523-714) antibodyTNIK 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TRAF2 and NCK Interacting Kinase (TNIK) (Internal Region) antibodyTNIK 适用: 人, 兔, 猴, Bat ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TRAF2 and NCK Interacting Kinase (TNIK) (Internal Region) antibodyTNIK 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Cow, 猴, Bat, 小鸡, Hamster IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-TRAF2 and NCK Interacting Kinase (TNIK) (AA 1-30), (N-Term) antibodyTNIK 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB3388 unconjugated
anti-TRAF2 and NCK Interacting Kinase (TNIK) (pSer769) antibodyTNIK 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TRAF2 and NCK Interacting Kinase (TNIK) (pSer764) antibodyTNIK 适用: 小鼠, 大鼠 ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunocytochemistry. Immunohistochemistry with formalin fixed paraffin embedded tissues: 2 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.7, containing 0.01 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-80 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- TNIK (TRAF2 and NCK Interacting Kinase (TNIK))
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别名
- TNIK
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背景
- TNIK is a MSN protein kinase that interacts with both TNF receptor-associated factor 2 (TRAF2) and the adapter protein NCK. The protein has been shown to activate the c-Jun N-terminal kinase pathway when overexpressed in Phoenix-A cells, and this activation is mediated solely by the C-terminal germinal center kinase homology region. TNIK has been shown to phosphorylate gelsolin, the principal intracellular and extracellular actin-severing protein, in vitro. This and evidence from mutational studies suggest that TNIK functions in the regulation of the cytoskeleton. At least eight splice isoforms have been reported. Northern analysis indicates TNIK expression in human heart, skeletal muscle, and brain, with lower levels of expression in kidney, liver, lung, and pancreas. ESTs have been isolated from human tissue libraries, including normal amnion, gallbladder, skin, and testis and cancerous bone, germ cell, nerve, and placenta.Synonyms: KIAA0551, TRAF2 and NCK-interacting protein kinase
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基因ID
- 23043
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UniProt
- Q9UKE5
抗原
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