GPR65 抗体
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北京 101111
Quick Overview for GPR65 抗体 (ABIN122422)
抗原
See all GPR65 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Reacts with T-Cell Death-Associated Gene 8 (family: GPCR, subfamily: Lysophospholipid/Lysosphingolipid)
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Immunoaffinity Chromatography
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免疫原
- Synthetic peptide - KLH conjugated
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anti-G Protein-Coupled Receptor 65 (GPR65) (AA 72-84), (Extracellular) antibody
GPR65 适用: 人 IHC, FACS, LCI, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 65 (GPR65) (Extracellular Domain) antibodyGPR65 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 65 (GPR65) (AA 72-84), (Extracellular) antibody (PE)GPR65 适用: 人 FACS 宿主: 兔 Polyclonal PE
anti-G Protein-Coupled Receptor 65 (GPR65) antibodyGPR65 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 65 (GPR65) (AA 72-84), (Extracellular) antibody (FITC)GPR65 适用: 人 FACS, LCI 宿主: 兔 Polyclonal FITC
anti-G Protein-Coupled Receptor 65 (GPR65) (C-Term) antibodyGPR65 适用: 人, 小鼠, 犬, 马, Pig, 兔, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 65 (GPR65) (3rd Extracellular Domain) antibodyGPR65 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 65 (GPR65) (3rd Cytoplasmic Domain) antibodyGPR65 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 65 (GPR65) (1st Cytoplasmic Domain) antibodyGPR65 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry with formalin fixed paraffin embedded tissues: 4-11 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.09 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-80 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- GPR65 (G Protein-Coupled Receptor 65 (GPR65))
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别名
- GPR65 / Psychosine Receptor
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背景
- GPR65 (TDAG8), a Lysophospholipid/Lysosphingolipid Receptor, is a molecular target for psychosine, a toxic lipid formed by the breakdown of galactosylceramide (cerebroside). A build-up of psychosine, caused by the lack of galactosylceramidase, results in the death of the myelin-synthesizing cells, oligodendrocytes, which is associated with Krabbe disease. Recent evidence suggests that GPR65 is one of the proton-sensing GPCRs coupling to adenylyl cyclase and psychosine and its related lysosphingolipids behave as if they were antagonists against protein-sensing receptors, including TDAG8, GPR4 and OGR1 GPR65 has been reported in human in peripheral blood leukocytes, spleen, lymph node, and thymus. ESTs have been isolated from human B-cell/lung/testis, brain/lung/testis, pancreas/spleen, lung/spleen, leukocyte, embryo, kidney, liver/spleen, thyroid, and vessel libraries.Synonyms: G-protein coupled receptor 65, T-cell death-associated protein 8, TDAG8
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基因ID
- 8477
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UniProt
- Q8IYL9
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途径
- cAMP Metabolic Process
抗原
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