CHRM3 抗体 (C-Term)
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Quick Overview for CHRM3 抗体 (C-Term) (ABIN122325)
抗原
See all CHRM3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Reacts with Muscarinic Acetylcholine Receptor M3 (Family: GPCR, Subfamily: Acetylcholine)
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交叉反应 (详细)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Peptide Immunogen Affinity Chromatography.
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免疫原
- Synthetic peptide - KLH conjugated
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应用备注
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Immunohistochemistry with formalin fixed paraffin embedded tissues: 72 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.7 containing 0.01 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch. -
有效期
- 12 months
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- CHRM3 (Cholinergic Receptor, Muscarinic 3 (CHRM3))
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别名
- Muscarinic Acetylcholine Receptor M3
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背景
- Muscarinic acetylcholine receptor 3 is an Acetylcholine Receptor that controls smooth muscle contraction by mediating phosphoinositide hydrolysis and Ca2+ mobilization. Activation of this receptor causes secretion in glandular tissues. Mouse studies suggest that the M3 receptor may play a role in appetite stimulation and food intake. Expression of this receptor has been reported in brain, eye, and heart. ESTs have been isolated from brain, colon, fetus, lung, and prostate libraries.Synonyms: CHRM3
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基因ID
- 1131
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UniProt
- P20309
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途径
- Synaptic Membrane
抗原
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