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GRM7 抗体 (N-Term)

GRM7 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN122320
发货至: 中国
  • 抗原 See all GRM7 抗体
    GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))
    抗原表位
    • 15
    • 8
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    N-Term
    适用
    • 52
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    • 5
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    宿主
    • 43
    • 11
    • 1
    克隆类型
    • 44
    • 11
    多克隆
    标记
    • 38
    • 3
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    • 2
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    This GRM7 antibody is un-conjugated
    应用范围
    • 43
    • 24
    • 12
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    • 7
    • 4
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    Reacts with Metabotropic Glutamate Receptor 7 (family: GPCR, subfamily: Metabotropic glutamate)
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Immunoaffinity Chromatography.
    免疫原
    Synthetic peptide - KLH conjugated
    Top Product
    Discover our top product GRM7 Primary Antibody
  • 应用备注
    Western Blot. Immunocytochemistry. Immunohistochemistry with formalin fixed paraffin embedded tissues: 6-16 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.09 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one monthor (in aliquots) at -20 °C to -70 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))
    别名
    mGluR7 / GRM7 (GRM7 产品)
    别名
    MGLUR7 antibody, GLUR7 antibody, GPRC1G antibody, MGLU7 antibody, 6330570A01Rik antibody, BB176677 antibody, C030018L03 antibody, E130018M02Rik antibody, Gpr1g antibody, Gprc1g antibody, mGluR7 antibody, glutamate metabotropic receptor 7 antibody, glutamate receptor, metabotropic 7 antibody, GRM7 antibody, Grm7 antibody
    背景
    Metabotropic Glutamate Receptor GRM7 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. GRM7 is highly concentrated at presynaptic terminals and is thought to play an important role in the modulation of glutamatergic synaptic transmission by effecting presynaptic inhibition of glutamate release. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group III includes GRM4, GRM6, GRM7, and GRM8 receptors, which are linked to inhibition of the cyclic AMP signaling cascade. Five mRNA variants of GRM7 have been described, most of the variants are expressed in brain and retina, although there are non-neuronal variants that may have different functional properties. GRM7 has been reported to be expressed in active zones of presynaptic axon terminals in various regions of the brain, eye, and spinal cord. Caution: GLUR7 refers to Ionotropic Glutamate Receptor 7, not to Metabotropic Glutamate Receptor 7 (mGLUR7).Synonyms: GPRC1G, MGLUR7, Metabotropic glutamate receptor 7
    基因ID
    2917
    UniProt
    Q14831
    途径
    Sensory Perception of Sound, cAMP Metabolic Process, Feeding Behaviour
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