HNF4 gamma 抗体
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北京 101111
Quick Overview for HNF4 gamma 抗体 (ABIN122270)
抗原
See all HNF4 gamma (HNF4G) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Reacts with Hepatocyte Nuclear Factor 4 Gamma (HNF4 Gamma/NR2A2) (family: NHR, subfamily: NR2 Hepatocyte NF4-like)
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纯化方法
- Peptide immunogen affinity column
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免疫原
- Synthetic peptide - KLH conjugated
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应用备注
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Immunohistochemistry with formalin fixed paraffin embedded tissues: 16-32 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International. -
限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.7, containing 0.01 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-80 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- HNF4 gamma (HNF4G) (Hepatocyte Nuclear Factor 4 gamma (HNF4G))
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别名
- HNF4 gamma / NR2A2
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背景
- Hepatocyte nuclear factor 4 gamma (HNF4 gamma) is a NR2 Hepatocyte NF4-Like receptor of relatively unknown function. Although HNF4 gamma is structurally related to HNF4 alpha and is expressed together with HNF 4 Alpha in pancreatic islets, it does not play a major role in the etiology of early onset, autosomal dominant, non insulin-dependent type 2 diabetes or maturity-onset diabetes of the young, MODY1. A pseudogene of HNF4 gamma, located on chromosome 13 (13q14.11 - 13q14.3), has been recently identified using a comparative genomics approach. HNF4 gamma expression has been reported human pancreas, kidney, testis, small intestine, and colon. ESTs have been isolated from human tissue libraries, including cancerous brain and colon, and normal brain,stomach, and liver. Ligand: Saturated and cis-monounsaturated C14-18 fatty acidsSynonyms: Hepatocyte nuclear factor 4-gamma, Nuclear receptor subfamily 2 group A member 2
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基因ID
- 3174
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UniProt
- Q14541
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途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
抗原
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