GNRHR 抗体
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北京 101111
Quick Overview for GNRHR 抗体 (ABIN122264)
抗原
See all GNRHR 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Reacts with Gonadotropin-Releasing Hormone Receptor (GnRHR) (family: GPCR, subfamily: Releasing hormone).
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纯化方法
- Peptide Immunogen Affinity Chromatography.
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免疫原
- Synthetic peptide - KLH conjugated
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应用备注
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Immunohistochemistry with formalin fixed paraffin embedded tissues: 1-2 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.09 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C forlonger. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))
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别名
- GnRH Receptor / GNRHR
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背景
- GnRHR is a Releasing-Hormone Receptor activated by gonadotropin-releasing hormone (GnRH). This receptor plays a major role in the regulation of reproductive functions. It modulates the synthesis and secretion of gonadotropin hormones such as luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary. In turn, LH and FSH regulate the release of steroid hormones from the gonads. Mutations in GnRHR have been linked to hypogonadotropic hypogonadism, a condition characterized by absence or delayed puberty and retarded bone maturation. GnRHR has been reported to be expressed mostly in the pituitary gonadotropes and in reproductive organs, including ovary, placenta, prostate, testis, and uterus. It is also expressed in breast, heart, kidney, liver, skeletal muscle, and thymus. No human ESTs have been isolated for this receptor.Synonyms: GRHR, GnRH-R, Gonadotropin-releasing hormone receptor
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基因ID
- 2798
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UniProt
- P30968
抗原
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