GPR3 抗体
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北京 101111
Quick Overview for GPR3 抗体 (ABIN122137)
抗原
See all GPR3 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Reacts with G Protein-Coupled Receptor GPR3 (family: GPCR, subfamily: Lysophospholipid/Lysosphingolipid)
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纯化方法
- Peptide immunogen affinity column
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免疫原
- Synthetic peptide - KLH conjugated
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应用备注
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Immunohistochemistry with formalin fixed paraffin embedded tissues: 6 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.7, containing 0.01 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-80 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- GPR3 (G Protein-Coupled Receptor 3 (GPR3))
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别名
- GPR3 / ACCA
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背景
- GPR3 has been identified as a constitutively active lysophospholipid/lysosphingolipid receptor. GPR3 receptor is a link in communication between the somatic cells and oocyte of the ovarian follicle where GPR3 maintains meiotic arrest in mouse oocytes. Oocytes from Gpr3 knockout mice resume meiosis within antral follicles, independently of an increase in luteinizing hormone, and this phenotype Mice deficient in GPR3 exhibit premature ovarian failure due to early oocyte aging. GPR3 has been reported at low abundance predominantly in the central nervous system and in the lung and kidney. ESTs have been isolated from brain and colon libraries.Synonyms: ACCA orphan receptor, G-protein coupled receptor 3
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基因ID
- 2827
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UniProt
- P46089
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途径
- cAMP Metabolic Process
抗原
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