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CysLTR1 抗体 (C-Term)

CYSLTR1 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN122044
发货至: 中国
  • 抗原 See all CysLTR1 (CYSLTR1) 抗体
    CysLTR1 (CYSLTR1) (Cysteinyl Leukotriene Receptor 1 (CYSLTR1))
    抗原表位
    • 10
    • 7
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    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 45
    • 6
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    • 2
    • 2
    • 2
    • 1
    • 1
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    • 1
    宿主
    • 44
    • 1
    克隆类型
    • 45
    多克隆
    标记
    • 30
    • 5
    • 3
    • 3
    • 2
    • 2
    This CysLTR1 antibody is un-conjugated
    应用范围
    • 35
    • 25
    • 19
    • 10
    • 10
    • 3
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    • 1
    • 1
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    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    Reacts with Cysteinyl Leukotriene Receptor 1 (family: GPCR, subfamily: Chemoattractant).
    交叉反应 (详细)
    Species reactivity (expected):MouseSpecies reactivity (tested):Human
    产品特性
    Synonyms: Cysteinyl leukotriene receptor 1, CysLTR1, LTD4 receptor, HG55, HMTMF81, Cysteinylleukotriene D4 receptor, G-protein coupled receptor HG55
    纯化方法
    Peptide immunogen affinity column
    免疫原
    Synthetic peptide - KLH conjugatedEpitope: C-terminal domain of humanGenename: CYSLTR1Remarks: The immunizing peptide shows 90 % identity (100 % similarity) with mouse and85 % identity (100 % similarity) with rat.
    Top Product
    Discover our top product CYSLTR1 Primary Antibody
  • 应用备注
    Immunohistochemistry with formalin fixed paraffin embedded tissues: 9-22 μg/mLAntigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove fromheat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween(TBST) for 1 min. at room temperature.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C forlonger. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch
    有效期
    12 months
  • 抗原
    CysLTR1 (CYSLTR1) (Cysteinyl Leukotriene Receptor 1 (CYSLTR1))
    别名
    CYSLTR1 (CYSLTR1 产品)
    别名
    zgc:112062 antibody, CYSLTR1 antibody, CYSLT1 antibody, CYSLT1R antibody, CYSLTR antibody, HMTMF81 antibody, BB147369 antibody, CysLT1R antibody, Cyslt1 antibody, cysLT1R antibody, cysteinyl leukotriene receptor 1 antibody, cysltr1 antibody, CYSLTR1 antibody, Cysltr1 antibody, LOC100338776 antibody
    背景
    Cysteinyl leukotriene receptor 1, a Chemoattractant Receptor, is detected in spleen, peripheral blood leukocytes, and lung smooth muscle (Lynch et al., 1999). It binds cysteinyl leukotrienes, which are neutrophil chemoattractants with potent proinflammatory action. Leukotrienes mediate many features of bronchial asthma such as edema, bronchial constriction, and hyperreactivity (Bisgaard et al., 2000). Selective CysLT1 antagonists are used to treat asthma. Ligand: The cysteinyl leukotrienes, leukotriene C4 (LTC4), leukotriene D4 (LTD4), and leukotriene E4 (LTE4) activate at least two receptors, CysLT1 and CysLT2, to mediate human bronchial asthma. LTC(4), LTD(4), and LTE(4) are a class of peptide-conjugated lipids formed from arachidonic acid and that are released during activation of mast cells.Synonyms: CysLTR1, Cysteinyl leukotriene D4 receptor, Cysteinyl leukotriene receptor 1, G-protein coupled receptor HG55, HG55, HMTMF81, LTD4 receptor
    基因ID
    10800
    UniProt
    Q9Y271
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