CysLTR1 抗体 (3rd Extracellular Domain)
Quick Overview for CysLTR1 抗体 (3rd Extracellular Domain) (ABIN122043)
抗原
See all CysLTR1 (CYSLTR1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- 3rd Extracellular Domain
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特异性
- Reacts with Cysteinyl Leukotriene Receptor 1(Family: GPCR, Subfamily: Chemoattractant).
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产品特性
- Synonyms: Cysteinyl leukotriene receptor 1, CysLTR1, LTD4 receptor, HG55, HMTMF81, Cysteinylleukotriene D4 receptor, G-protein coupled receptor HG55
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纯化方法
- Peptide immunogen affinity column
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免疫原
- Synthetic peptide - KLH conjugatedEpitope: 3rd extracellular domain of humanGenename: CYSLTR1Remarks: The immunizing peptide shows 80 % identity (85 % similarity) with mouse and75 % identity (90 % similarity) with rat.
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anti-Cysteinyl Leukotriene Receptor 1 (CYSLTR1) (AA 298-337) antibody
CYSLTR1 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cysteinyl Leukotriene Receptor 1 (CYSLTR1) (Extracellular Domain) antibodyCYSLTR1 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cysteinyl Leukotriene Receptor 1 (CYSLTR1) (Internal Region) antibodyCYSLTR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cysteinyl Leukotriene Receptor 1 (CYSLTR1) antibodyCYSLTR1 适用: 人, 猴 WB, IF, IHC, IC 宿主: 兔 Polyclonal unconjugated
anti-Cysteinyl Leukotriene Receptor 1 (CYSLTR1) (AA 248-337) antibodyCYSLTR1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cysteinyl Leukotriene Receptor 1 (CYSLTR1) (AA 131-180) antibodyCYSLTR1 适用: 人 WB, ELISA, IF, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cysteinyl Leukotriene Receptor 1 (CYSLTR1) antibodyCYSLTR1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Cysteinyl Leukotriene Receptor 1 (CYSLTR1) (Internal Region) antibodyCYSLTR1 适用: 人, 猴 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cysteinyl Leukotriene Receptor 1 (CYSLTR1) (AA 199-248) antibodyCYSLTR1 适用: 人, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Cysteinyl Leukotriene Receptor 1 (CYSLTR1) (AA 1-100) antibodyCYSLTR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry with formalin fixed paraffin embedded tissues: 6 -14g/mL. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove fromheat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween(TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, containing 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-80 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- CysLTR1 (CYSLTR1) (Cysteinyl Leukotriene Receptor 1 (CYSLTR1))
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别名
- CYSLTR1
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背景
- Cysteinyl leukotriene receptor 1, a Chemoattractant Receptor, is detected in spleen, peripheral blood leukocytes, and lung smooth muscle (Lynch et al., 1999). It binds cysteinyl leukotrienes, which are neutrophil chemoattractants with potent proinflammatory action. Leukotrienes mediate many features of bronchial asthma such as edema, bronchial constriction, and hyperreactivity (Bisgaard et al., 2000). Selective CysLT1 antagonists are used to treat asthma. The cysteinyl leukotrienes, leukotriene C4 (LTC4), leukotriene D4 (LTD4), and leukotriene E4 (LTE4) activate at least two receptors, CysLT1 and CysLT2, to mediate human bronchial asthma. LTC(4), LTD(4), and LTE(4) are a class of peptide-conjugated lipids formed from arachidonic acid and that are released during activation of mast cells.Synonyms: CysLTR1, Cysteinyl leukotriene D4 receptor, Cysteinyl leukotriene receptor 1, G-protein coupled receptor HG55, HG55, HMTMF81, LTD4 receptor
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基因ID
- 10800
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UniProt
- Q9Y271
抗原
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