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HTR1F 抗体 (C-Term)

The 兔 多克隆 anti-HTR1F antibody (ABIN121983) specifically detects HTR1F in IHC (p). The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN121983
发货至: 中国
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Quick Overview for HTR1F 抗体 (C-Term) (ABIN121983)

抗原

See all HTR1F 抗体
HTR1F (5-Hydroxytryptamine (serotonin) Receptor 1F (HTR1F))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

  • 44
多克隆

标记

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This HTR1F antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    C-Term

    特异性

    This antibody detects human Serotonin receptor 1F (HTR1F) at C-term. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except HTR1E (71 %), HTR1D (59 %), HTR1B (59 %).

    交叉反应 (详细)

    Species reactivity (expected):Mouse, Rat (see 'Immunogen Remarks')Species reactivity (tested):Human

    纯化方法

    Immunoaffinity chromatography

    免疫原

    Synthetic peptide - KLH conjugated
  • 应用备注

    Immunohistochemstry on paraffin embedded sections: 2-3 μg/mL. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.09 % Sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-80 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
    Shelf Life: one year from despatch.

    有效期

    12 months
  • 抗原

    HTR1F (5-Hydroxytryptamine (serotonin) Receptor 1F (HTR1F))

    别名

    Serotonin Receptor 1F (HTR1F)

    背景

    5-HT1F, a Serotonin Receptor, is negatively coupled to adenylate cyclase. Selective 5-HT1F agonists may prove therapeutic in the treatment of migraine headache, lacking the side effects associated with the agonists of the 5-HT1B and 5-HT1D receptors. Expression of the 5-HT1F receptor has been reported in various brain structures, including cortex, hippocampus, trigeminal ganglia, and cerebral blood vessels. Expression in peripheral tissues is limited to uterus, mesentery, and artery. No expression has been detected in heart, kidney, liver, pancreas, or spleen.Synonyms: 5-HT-1F, 5-hydroxytryptamine receptor 1F, HTR1EL

    基因ID

    3355

    UniProt

    P30939

    途径

    JAK/STAT Signaling
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